Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.92 |
| ▸ | TP53 | P04637 | 1/20 | 0.92 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.75 |
| ▸ | CA1 | P00915 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA3 | P07451 | 1/20 | 0.71 |
| ▸ | TYR | P14679 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | CA4 | P22748 | 1/20 | 0.71 |
| ▸ | CA6 | P23280 | 1/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.71 |
| ▸ | CA7 | P43166 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.71 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.69 |
| ▸ | DAO | P14920 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL5083220 | 1.00 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL156613 | 1.00 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL3038255 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL9250012 | 0.96 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL175823 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1655 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL25381766 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL9484769 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1663 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025229586-A1 | POLYAMIDE GREASE THICKENING AGENT | INV NYLON CHEMICALS AMERICAS, LLC (US) | 2025-11-06 | — | — | WO | claimed |
| CN-112074974-B | Particulate silicon-containing active material, negative electrode, lithium ion battery cell, transportation vehicle, and method of making active material and electrode | 大众汽车股份公司 | 2024-01-23 | — | — | CN | claimed |
| CN-112641995-B | Chiral hydrogel dressing with antibacterial and repair promoting functions and preparation method and application thereof | 上海交通大学 | 2021-11-23 | — | — | CN | claimed |
| CN-113637210-A | Gas-barrier moisture-permeable film and preparation method and application thereof | 中国石油化工股份有限公司 | 2021-11-12 | — | — | CN | claimed |
| CN-113634136-A | Nanofiltration membrane and preparation method and application thereof | 中国石油化工股份有限公司 | 2021-11-12 | — | — | CN | claimed |
| CN-110358081-B | Preparation method of aromatic polyamide high polymer containing sulfonic group and having higher molecular weight | 东华大学 | 2021-11-09 | — | — | CN | claimed |
| CN-112973473-A | Reverse osmosis composite membrane resisting biological pollution and preparation method thereof | 天津工业大学 | 2021-06-18 | — | — | CN | claimed |
| CN-112641995-A | Chiral hydrogel dressing with antibacterial and repair promoting functions and preparation method and application thereof | 上海交通大学 | 2021-04-13 | — | — | CN | claimed |
| EP-3785315-A1 | PARTICULATE SILICON-CONTAINING ACTIVE MATERIAL, NEGATIVE ELECTRODE, LITHIUM-ION BATTERY CELL, VEHICLE AND PROCESS FOR PRODUCING ACTIVE MATERIAL AND ELECTRODE | VOLKSWAGEN AKTIENGESELLSCHAFT (DE) | 2021-03-03 | — | — | EP | claimed |
| CN-112074974-A | Particulate silicon-containing active material, negative electrode, lithium ion battery cell, transportation vehicle, and methods of manufacturing active material and electrode | 大众汽车股份公司 | 2020-12-11 | — | — | CN | claimed |
| EP-0040177-B1 | PROCESS FOR THE PREPARATION OF BENZENE OR NAPHTHALENE ALKENYL CARBOXYLIC ACID DERIVATIVES | CIBA-GEIGY AG (CH) | 1983-07-20 | — | — | EP | claimed |
| EP-0023662-B1 | HEAT-RESISTENT POSITIVE PHOTORESISTS AND PROCESS FOR THE PREPARATION OF HEAT-RESISTENT RELIEF STRUCTURES | SIEMENS AKTIENGESELLSCHAFT (DE) | 1983-05-18 | — | — | EP | claimed |
| US-4335055-A | Process for the preparation of alkenylbenzene derivatives or alkenylnaphthalene derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | claimed |
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | claimed |
| US-4278786-A | BIS/P-AMINOPHENOL ETHER OF A BISPHENOL | HITACHI, LTD. (JP) | 1981-07-14 | — | — | US | claimed |
| US-4277576-A | Preparation of modified polymers of N-vinylpyrrolid-2-one and their use for the preparation of polymers interrupted by bridge members | BASF AKTIENGESELLSCHAFT (DE) | 1981-07-07 | — | — | US | claimed |
| US-4169932-A | METHOD OF PRODUCING POLY-P-PHENYLENETEREPHTHALAMIDE OR ITS COPOLYMERS | INGERSOLL EQUIPMENT CO., INC., | 1979-10-02 | — | — | US | claimed |
| US-4100116-A | AMINATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-11 | — | — | US | claimed |
| US-4091017-A | FRIEDEL-CRAFTS CATALYSTS, HYDROLYSIS | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1978-05-23 | — | — | US | claimed |
| US-4006120-A | Thermostable polyester | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | claimed |