Scyllitol

Scyllitol

SCHEMBL187397

O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 1.00
▸ APP P05067 1/20 1.00
▸ GBA1 P04062 4/20 0.50
▸ MGAM O43451 6/20 0.33
▸ FUCA1 P04066 5/20 0.33
▸ GLA P06280 2/20 0.33
▸ GANC Q8TET4 2/20 0.33
▸ GAA P10253 2/20 0.33
▸ SI P14410 1/20 0.31
▸ MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2512806 1.00 LMNA (1.00) LMNAAPPGBA1MGAMFUCA1
Scyllitol SCHEMBL13207905 1.00 LMNA (1.00) LMNAAPPGBA1MGAMFUCA1
Scyllitol SCHEMBL12711208 1.00 LMNA (1.00) LMNAAPPGBA1MGAMFUCA1
Scyllitol SCHEMBL187278 1.00 LMNA (1.00) LMNAAPPGBA1MGAMFUCA1
Scyllitol SCHEMBL1055883 1.00 LMNA (1.00) LMNAAPPGBA1MGAMFUCA1
Scyllitol SCHEMBL21388397 1.00 LMNA (1.00) LMNAAPPGBA1MGAMFUCA1
Scyllitol SCHEMBL13058696 1.00 LMNA (1.00) LMNAAPPGBA1MGAMFUCA1
Scyllitol SCHEMBL12735687 1.00 LMNA (1.00) LMNAAPPGBA1MGAMFUCA1
SCHEMBL2511997 1.00 — —
Inositol SCHEMBL2422938 1.00 LMNA (1.00) LMNAAPPGBA1MGAMFUCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 498 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12226488-B2 Nitroreductase-releasable pro-drugs and methods for using the same ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2025-02-18 — — US claimed
EP-3542810-B1 COMPOSITION CONTAINING ARTEMISIA ANNUA EXTRACT AS EFFECTIVE INGREDIENT FOR ALLEVIATING SKIN DISEASE AND PREPARATION METHOD THEREFOR KOREA INST SCI & TECH (KR) 2023-05-24 — — EP claimed
EP-4076403-A1 GASTRO-RESISTANT MICROPARTICLES COMPRISING INOSITOL AND/OR GYMNEMA SYLVESTRE EXTRACT, PHARMACEUTICAL AND NUTRACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF IDI Integratori Dietetici Italiani S.r.l. (IT) 2022-10-26 — — EP claimed
EP-4034092-A1 SCYLLO-INOSITOL AND ITS USE AS INSULIN SENSITIZER Société des Produits Nestlé S.A. (CH) 2022-08-03 — — EP claimed
US-20220211854-A1 NITROREDUCTASE-RELEASABLE PRO-DRUGS AND METHODS FOR USING THE SAME ARIZONA BOARD OF REGENTS on behalf of THE UNIVERSITY OF ARIZONA, A BODY CORPORATE (US) 2022-07-07 — — US claimed
EP-4021429-A1 SCYLLO-INOSITOL AND B-CELL MEDIATED DISORDERS Société des Produits Nestlé S.A. (CH) 2022-07-06 — — EP claimed
US-20220144747-A1 SHIKIMATE ANALOGUES AND METHODS OF USE THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA 2022-05-12 — — US claimed
WO-2022081521-A1 INOSITOL-BISPYROPHOSPHATE-DERIVED COMPOUNDS AND USES THEREOF NICOLAU YVES CLAUDE (US) 2022-04-21 — — WO claimed
WO-2021124244-A1 GASTRO-RESISTANT MICROPARTICLES COMPRISING INOSITOL AND/OR GYMNEMA SYLVESTRE EXTRACT, PHARMACEUTICAL AND NUTRACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF IDI INTEGRATORI DIETETICI ITALIANI S.R.L. (IT) 2021-06-24 — — WO claimed
WO-2021058628-A1 SCYLLO-INOSITOL AND ITS USE AS INSULIN SENSITIZER Société des Produits Nestlé SA (CH) 2021-04-01 — — WO claimed
WO-1998057620-A2 INOSITOL FOR MODULATION OF IMMUNE RESPONSE CEDARS-SINAI MEDICAL CENTER (US) 1998-12-23 — — WO claimed
WO-1997034853-A1 PHOSPHORYLATION PROCESS AND CATALYST PERSTORP AB (SE) 1997-09-25 — — WO claimed
EP-0505452-B1 USE OF INOSITOLPHOSPHATES FOR PREPARING MEDICAMENT PERSTORP AB (SE) 1996-06-19 — — EP claimed
EP-0663915-A1 SYNTHESES OF D-CHIRO-3-INOSOSE AND (+)-D-CHIRO-INOSITOL VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 1995-07-26 — — EP claimed
WO-1994007897-A1 SYNTHESES OF D-CHIRO-3-INOSOSE AND (+)-D-CHIRO-INOSITOL VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 1994-04-14 — — WO claimed
US-5217959-A Method of treating multiple sclerosis with phytic acid JARIWALLA, RAXIT 1993-06-08 — — US claimed
US-5112814-A Method of treatment of Parkinson's disease using phytic acid SABIN ROBERT (US) 1992-05-12 — — US claimed
EP-0420428-A2 Mehod of treatment of rheumatoid arthritis using phytic acid Sabin, Robert (US) 1991-04-03 — — EP claimed
US-4952396-A OR SALTS OR HYDROLYZATES; ORAL ADMINISTRATION LINUS PAULING INSTITUTE OF SCIENCE & MEDICINE (US) 1990-08-28 — — US claimed
US-4847082-A Method of treatment of Alzheimer's disease using phytic acid Sabin, Robert (US) 1989-07-11 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12226488-B2 Nitroreductase-releasable pro-drugs and methods for using the same AKR1B1, AKR1A1, POR LMNA 1971/4885APP 3921/4885GBA1 3358/4885
US-20220211854-A1 NITROREDUCTASE-RELEASABLE PRO-DRUGS AND METHODS FOR USING THE SAME AKR1B1, AKR1A1, POR LMNA 1971/4885APP 3921/4885GBA1 3358/4885
US-20220144747-A1 SHIKIMATE ANALOGUES AND METHODS OF USE GRIK5, GRIK1, GRIK3 LMNA 4673/4885APP 2388/4885GBA1 4096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback