Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.36 |
| ▸ | LCK | P06239 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28616211 | 0.91 | PLAT (0.38) | PLATLMNA | |
| SCHEMBL13732362 | 0.87 | RIPK2 (0.45) | RIPK2LCKKDRTGFBR1LMNA | |
| SCHEMBL18740086 | 0.83 | PLAT (0.40) | PLATRIPK2LCKKDRTGFBR1 | |
| SCHEMBL25456250 | 0.72 | RIPK2 (0.45) | RIPK2LCKKDRTGFBR1 | |
| SCHEMBL28617359 | 0.67 | PLAT (0.34) | PLATRIPK2LCKKDRTGFBR1 | |
| SCHEMBL25144842 | 0.67 | RIPK2 (0.47) | RIPK2LCKKDRTGFBR1 | |
| SCHEMBL18739970 | 0.64 | NOX4 (0.37) | TSHR | |
| SCHEMBL25456489 | 0.64 | RIPK2 (0.45) | RIPK2LCKKDRTGFBR1 | |
| SCHEMBL21081513 | 0.61 | MAPK1 (0.46) | PLATLMNATSHRNPSR1 | |
| SCHEMBL18740127 | 0.60 | NOTUM (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473497-B | EP4 antagonists | 卫材R&D 管理有限公司 | 2021-09-10 | — | — | CN | disclosed |
| EP-3362454-A1 | EP4 ANTAGONISTS | Eisai R&D Management Co., Ltd. (JP) | 2018-08-22 | — | — | EP | disclosed |
| WO-2017066633-A1 | EP4 ANTAGONISTS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-04-20 | — | — | WO | disclosed |