Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28616211 | 0.76 | PLAT (0.38) | PLATLMNA | |
| SCHEMBL28792087 | 0.73 | PLAT (0.35) | PLATPOLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3979902 | 0.67 | BTK (0.34) | PLATPOLBMEN1KMT2A | |
| SCHEMBL18740108 | 0.67 | PLAT (0.36) | PLATLMNARIPK2LCKKDR | |
| SCHEMBL18209768 | 0.65 | ALOX5 (0.48) | — | |
| SCHEMBL21130895 | 0.64 | PDE4D (0.41) | PLATCYP1A2TDP1L3MBTL1LMNA | |
| SCHEMBL22102662 | 0.63 | — | — | |
| SCHEMBL20748895 | 0.62 | TLR9 (0.42) | TGFBR1 | |
| SCHEMBL20691669 | 0.60 | MAPK1 (0.37) | POLBMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL1335845 | 0.59 | KDM4E (0.60) | POLBCYP1A2CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473497-B | EP4 antagonists | 卫材R&D 管理有限公司 | 2021-09-10 | — | — | CN | disclosed |