Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.40 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | FES | P07332 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | ROS1 | P08922 | 1/20 | 0.39 |
| ▸ | FER | P16591 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1874087 | 1.00 | MASP2 (0.47) | MASP2CHRNA7KLKB1METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL1874541 | 0.99 | MASP2 (0.46) | MASP2CHRNA7KLKB1METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL1874544 | 0.99 | MASP2 (0.46) | MASP2CHRNA7KLKB1METAP2METAP1 | |
| SCHEMBL1870166 | 0.85 | MASP2 (0.47) | MASP2CHRNA7KLKB1METTL3METTL14 | |
| SCHEMBL1867873 | 0.80 | MASP2 (0.45) | MASP2CHRNA7KLKB1METTL3METTL14 | |
| SCHEMBL1868978 | 0.80 | MASP2 (0.44) | MASP2CHRNA7KLKB1ABL1JAK2 | |
| SCHEMBL1901151 | 0.78 | MASP2 (0.45) | MASP2METAP2METAP1METTL3NAMPT | |
| SCHEMBL1901155 | 0.78 | MASP2 (0.45) | MASP2METAP2METAP1METTL3NAMPT | |
| SCHEMBL1870522 | 0.78 | MASP2 (0.45) | MASP2CHRNA7KLKB1METTL3METTL14 | |
| Trifluoroacetic Acid SCHEMBL1873628 | 0.76 | MASP2 (0.43) | MASP2CHRNA7KLKB1METTL3METTL14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |