SCHEMBL18742136

SCHEMBL18742136

CCCCCCC(=O)N[C@@H](C)C(=O)OCC

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.62
KMT2A Q03164 3/20 0.62
MEN1 O00255 1/20 0.62
MAPK1 P28482 1/20 0.62
DNM1 Q05193 1/20 0.51
NOD1 Q9Y239 3/20 0.50
HSP90AA1 P07900 1/20 0.48
PLA2G10 O15496 1/20 0.48
POLB P06746 1/20 0.47
PLA2G2C Q5R387 1/20 0.47
ASAH2 Q9NR71 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17010250 1.00 FAAH (0.62) FAAHKMT2AMEN1MAPK1DNM1
SCHEMBL18742133 1.00 FAAH (0.62) FAAHKMT2AMEN1MAPK1DNM1
SCHEMBL3271592 1.00 FAAH (0.62) FAAHKMT2AMEN1MAPK1DNM1
SCHEMBL7154001 1.00 FAAH (0.62) FAAHKMT2AMEN1MAPK1DNM1
SCHEMBL3271401 1.00 FAAH (0.62) FAAHKMT2AMEN1MAPK1DNM1
SCHEMBL16474 0.98 FAAH (0.59) FAAHKMT2AMEN1MAPK1DNM1
SCHEMBL7153526 0.88 FAAH (0.61) FAAHKMT2AMEN1MAPK1DNM1
SCHEMBL7155465 0.88 FAAH (0.61) FAAHKMT2AMEN1MAPK1DNM1
SCHEMBL7150166 0.88 FAAH (0.61) FAAHKMT2AMEN1MAPK1DNM1
SCHEMBL30876484 0.88 FAAH (0.61) FAAHKMT2AMEN1MAPK1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10577459-B2 Aliphatic poly(ester)s with thiol pendant groups WISTRAND, Anna (SE) 2020-03-03 US disclosed
US-20180305495-A1 ALIPHATIC POLY(ESTER)S WITH THIOL PENDANT GROUPS PAPPALARDO, Daniela (IT) 2018-10-25 US disclosed
EP-3362500-A1 ALIPHATIC POLY(ESTER)S WITH THIOL PENDANT GROUPS Novus Scientific AB (SE) 2018-08-22 EP disclosed
WO-2017064291-A1 ALIPHATIC POLY(ESTER)S WITH THIOL PENDANT GROUPS NOVUS SCIENTIFIC AB (SE) 2017-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10577459-B2 Aliphatic poly(ester)s with thiol pendant groups PARG, TST, CBS FAAH 1615/4885KMT2A 2225/4885MEN1 3136/4885
US-20180305495-A1 ALIPHATIC POLY(ESTER)S WITH THIOL PENDANT GROUPS PARG, TST, CBS FAAH 1615/4885KMT2A 2225/4885MEN1 3136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.