Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | ALPI | P09923 | 1/20 | 0.30 |
| ▸ | ALPG | P10696 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13588042 | 0.79 | EPHX1 (0.36) | RAB9AKMT2AKDM4ECYP2C9SMN1; SMN2 | |
| SCHEMBL28895183 | 0.73 | RAB9A (0.34) | RAB9AALDH1A1KMT2AKDM4ECYP2C9 | |
| SCHEMBL28592120 | 0.72 | TDP1 (0.35) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL969173 | 0.72 | NPC1 (0.46) | RAB9AMMP1MMP2MMP3MMP9 | |
| SCHEMBL23396753 | 0.70 | POLB (0.42) | RAB9AMMP1MMP2MMP9MMP8 | |
| SCHEMBL11950246 | 0.70 | EPHX1 (0.34) | RAB9AKMT2AKDM4ECYP2C9SMN1; SMN2 | |
| SCHEMBL10760000 | 0.70 | ALDH1A1 (0.38) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL6859267 | 0.69 | KDM4E (0.46) | RAB9AALDH1A1KMT2AKDM4ECYP2C9 | |
| SCHEMBL27832109 | 0.69 | ALDH1A1 (0.44) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL138082 | 0.69 | EPHX1 (0.41) | RAB9AALDH1A1KMT2AKDM4ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017062688-A1 | WNT SIGNALING PATHWAY INHIBITORS AND THERAPEUTIC APPLICATIONS THEREOF | Suzhou Yunxuan Yiyao Keji Youxian Gongsi (CN) | 2017-04-13 | — | — | WO | disclosed |