Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.32 |
| ▸ | DRD4 | P21917 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17789034 | 0.99 | DRD4 (0.32) | MAPTSIGMAR1DRD4DRD2BRPF1 | |
| SCHEMBL17789036 | 0.88 | CNR2 (0.39) | KDM4E | |
| SCHEMBL17792575 | 0.85 | KDM4E (0.36) | MAPTPABPC1ALDH1A1KDM4EALOX15 | |
| SCHEMBL17789055 | 0.79 | BRPF1 (0.38) | MAPTSIGMAR1DRD4DRD2BRPF1 | |
| SCHEMBL17789037 | 0.76 | DRD4 (0.34) | SIGMAR1DRD4DRD2MEN1KMT2A | |
| SCHEMBL17792540 | 0.74 | MTNR1B (0.36) | KMT2AALDH1A1 | |
| SCHEMBL17789027 | 0.71 | ALDH1A1 (0.37) | MAPTDRD4DRD2ALDH1A1KDM4E | |
| SCHEMBL17789035 | 0.67 | DAO (0.44) | DRD4DRD2MEN1KMT2A | |
| SCHEMBL8135888 | 0.66 | DRD4 (0.55) | DRD4DRD2MEN1KMT2AALDH1A1 | |
| SCHEMBL17792545 | 0.65 | ALDH1A1 (0.39) | MAPTBRPF1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624205-B2 | Substituted 6,5-fused bicyclic heteroaryl compounds | Epizyme, Inc. (US) | 2017-04-18 | — | — | US | disclosed |