Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | EIF4E | P06730 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TOP1 | P11387 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | PNP | P00491 | 3/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ATG7 | O95352 | 4/20 | 0.37 |
| ▸ | NT5E | P21589 | 2/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | ATIC | P31939 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15788414 | 0.89 | LMNA (0.59) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL17232092 | 0.79 | LMNA (0.46) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL18744101 | 0.79 | PNP (0.70) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL12151510 | 0.78 | LMNA (0.73) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL25520855 | 0.78 | LMNA (0.73) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL15788460 | 0.78 | PNP (0.59) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL12879138 | 0.77 | LMNA (0.68) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL12879143 | 0.77 | LMNA (0.68) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL15031296 | 0.74 | LMNA (0.74) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL14546644 | 0.74 | LMNA (0.74) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624249-B2 | Nucleoside kinase bypass compositions and methods | MERCK SHARP & DOHME CORP. (US) | 2017-04-18 | — | — | US | disclosed |