Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 18/20 | 0.43 |
| ▸ | RXRA | P19793 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18929535 | 1.00 | TDP1 (0.43) | TDP1RXRAALDH1A1HASPIN | |
| SCHEMBL11149457 | 0.86 | ALDH1A1 (0.44) | TDP1RXRAALDH1A1 | |
| SCHEMBL24167474 | 0.83 | TDP1 (0.44) | TDP1RXRAALDH1A1 | |
| SCHEMBL17798767 | 0.81 | TDP1 (0.50) | TDP1RXRAALDH1A1 | |
| SCHEMBL11146401 | 0.75 | ALDH1A1 (0.48) | TDP1ALDH1A1 | |
| SCHEMBL11149438 | 0.75 | ALDH1A1 (0.44) | TDP1ALDH1A1 | |
| SCHEMBL11149357 | 0.75 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL11264592 | 0.73 | ALDH1A1 (0.54) | TDP1RXRAALDH1A1 | |
| SCHEMBL11148463 | 0.71 | ALDH1A1 (0.44) | TDP1ALDH1A1 | |
| SCHEMBL11147190 | 0.71 | ALDH1A1 (0.44) | TDP1RXRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9803047-B2 | Alternating ring-opening metathesis polymerization | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-10-31 | — | — | US | disclosed |
| US-9624338-B2 | Alternating ring-opening metathesis polymerization | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-04-18 | — | — | US | disclosed |