Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | THRA | P10827 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | SCN1A | P35498 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | PHF2 | O75151 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18744670 | 0.90 | KDM5A (0.53) | SIRT3CYP3A4THRATHRBALDH1A1 | |
| SCHEMBL18744699 | 0.86 | KDM5A (0.60) | SIRT3CYP3A4THRATHRBALDH1A1 | |
| SCHEMBL15313186 | 0.82 | SIRT3 (0.66) | SIRT3CYP3A4THRATHRBALDH1A1 | |
| SCHEMBL18744672 | 0.81 | EYA3 (0.43) | CYP3A4THRBALDH1A1CYP1A2HRH3 | |
| SCHEMBL18744679 | 0.77 | EYA3 (0.39) | SIRT3CYP3A4THRATHRBALDH1A1 | |
| SCHEMBL19879490 | 0.75 | SIRT3 (0.59) | SIRT3CYP3A4THRATHRBALDH1A1 | |
| SCHEMBL18744671 | 0.74 | KDM5A (0.46) | SIRT3CYP3A4THRATHRBALDH1A1 | |
| SCHEMBL18743965 | 0.73 | EYA3 (0.58) | SIRT3THRATHRBKDM5AKDM7A | |
| SCHEMBL15313193 | 0.72 | KDM5A (0.76) | SIRT3CYP3A4THRATHRBALDH1A1 | |
| SCHEMBL15314890 | 0.72 | SMPD1 (0.69) | SIRT3CYP3A4THRATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9895340-B2 | Fluorinated benzofuran derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| US-20170189370-A1 | FLUORINATED BENZOFURAN DERIVATIVES | FELIQS CORPORATION (JP) | 2017-07-06 | — | — | US | disclosed |
| US-9624189-B2 | Fluorinated benzofuran derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189370-A1 | FLUORINATED BENZOFURAN DERIVATIVES | FABP3, TNNI3, TNNT2 | SIRT3 153/4885CYP3A4 89/4885THRA 4073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.