Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18745578 | 0.76 | NFE2L2 (0.55) | NFE2L2KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL28331815 | 0.76 | NFE2L2 (0.55) | NFE2L2KMT2AALDH1A1LMNAHTT | |
| SCHEMBL13096609 | 0.76 | NFE2L2 (0.55) | NFE2L2KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7374925 | 0.76 | NFE2L2 (0.55) | NFE2L2KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL20149020 | 0.75 | NR1H2 (0.45) | LMNAHTTNPSR1SMN1; SMN2 | |
| Water SCHEMBL28134264 | 0.75 | NFE2L2 (0.70) | NFE2L2ALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL12766982 | 0.74 | MAPK1 (0.52) | KMT2AALDH1A1MAPK1NPSR1MEN1 | |
| SCHEMBL10139336 | 0.74 | MAPK1 (0.52) | KMT2AALDH1A1MAPK1NPSR1MEN1 | |
| SCHEMBL10139335 | 0.74 | MAPK1 (0.52) | KMT2AALDH1A1MAPK1NPSR1MEN1 | |
| SCHEMBL28076993 | 0.73 | NFE2L2 (0.52) | NFE2L2KMT2AALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624209-B2 | Substituted phenylureas and phenylamides as vanilloid receptor ligands | GRUENENTHAL GMBH (DE) | 2017-04-18 | — | — | US | disclosed |