SCHEMBL18746

SCHEMBL18746

O=C(O)c1cc(-c2cc(C(=O)O)c3ccccc3n2)nc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.83
LMNA P02545 2/20 0.83
SMN1; SMN2 Q16637 2/20 0.83
PDE10A Q9Y233 1/20 0.83
NPC1 O15118 1/20 0.81
RAB9A P51151 1/20 0.81
DHODH Q02127 4/20 0.77
MEN1 O00255 3/20 0.73
KMT2A Q03164 3/20 0.73
POLB P06746 3/20 0.73
ALDH1A1 P00352 2/20 0.69
GLA P06280 2/20 0.69
GAA P10253 2/20 0.69
AKR1C3 P42330 1/20 0.69
AKR1C2 P52895 1/20 0.69
AKR1C1 Q04828 1/20 0.69
ESR1 P03372 1/20 0.69
TP53 P04637 1/20 0.69
HPGD P15428 1/20 0.69
MAPK1 P28482 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29359819 1.00 KDM4E (0.83) KDM4ELMNASMN1; SMN2PDE10ANPC1
Potassium SCHEMBL93448 0.98 KDM4E (0.80) KDM4ELMNASMN1; SMN2PDE10ANPC1
SCHEMBL30595092 0.98 KDM4E (0.80) KDM4ELMNASMN1; SMN2PDE10ANPC1
SCHEMBL7962360 0.98 KDM4E (0.80) KDM4ELMNASMN1; SMN2PDE10ANPC1
SCHEMBL374556 0.98 KDM4E (0.80) KDM4ELMNASMN1; SMN2PDE10ANPC1
SCHEMBL374558 0.98 KDM4E (0.80) KDM4ELMNASMN1; SMN2PDE10ANPC1
SCHEMBL14518624 0.93 NPC1 (0.77) KDM4ELMNASMN1; SMN2PDE10ANPC1
SCHEMBL12131245 0.91 KDM4E (0.71) KDM4ELMNASMN1; SMN2PDE10ANPC1
Cinchophen SCHEMBL7588217 0.91 KDM4E (1.00) KDM4ELMNASMN1; SMN2PDE10ANPC1
Cinchophen SCHEMBL25519 0.91 KDM4E (1.00) KDM4ELMNASMN1; SMN2PDE10ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 24152 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026105085-A1 HYGIENE MONITORING DEVICE, ELECTRONIC OPTICAL READER APPARATUS AND RELATED METHOD TERRAGENE S.A. (UY) 2026-05-21 WO claimed
EP-4698205-A1 PHARMACEUTICAL FORMULATIONS FOR LONGEVITY IN MAMMALS Cellular Longevity, Inc. (US) 2026-02-25 EP claimed
US-12558379-B2 Compositions and methods relating to pooled fetal support tissue BIOTISSUE HOLDINGS INC. (US) 2026-02-24 US claimed
US-20260042084-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP GENERAL ELECTRIC TECHNOLOGY GMBH (CH) 2026-02-12 US claimed
EP-4677363-A1 TUMOR RESIDENT PROTEIN MARKER PANEL FOR PREDICTING RECURRENCE IN BILE DUCT CANCER PATIENTS Albert-Ludwigs-Universität Freiburg Körperschaft des öffentlichen Rechts (DE) 2026-01-14 EP claimed
US-20260008809-A1 PROTEIN PURIFICATION NUCLERA LTD (GB) 2026-01-08 US claimed
US-12510545-B2 Method and composition for rapid detection of protein soils ECOLAB USA INC. (US) 2025-12-30 US claimed
WO-2025244838-A1 IMPROVED COLLAGEN COATINGS CORNING INCORPORATED (US) 2025-11-27 WO claimed
WO-2025238576-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION Nuovo Pignone Tecnologie – S.r.l. (IT) 2025-11-20 WO claimed
US-20250354659-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION NUOVO PIGNONE TECNOLOGIE – S R L (IT) 2025-11-20 US claimed
US-5491093-A Quantitative determination of lipid, and of co-existing two compounds CANON KABUSHIKI KAISHA (JP) 1996-02-13 US claimed
US-5443981-A Membrane fraction from leaf sheath tissue of grass species RUTGERS, THE STATE UNIVERSITY (US) 1995-08-22 US claimed
EP-0557350-B1 ASSAY FOR GLYCATED BLOOD PROTEINS AXIS BIOCHEMICALS AS (NO) 1994-10-05 EP claimed
WO-1994007911-A1 METHOD AND KIT FOR ISOLATION AND PURIFICATION OF ENZYME-ANTIBODY CONJUGATES PIERCE CHEMICAL COMPANY (US) 1994-04-14 WO claimed
US-5266686-A Method for isolation and purification of enzyme-antibody conjugates PIERCE CHEMICAL COMPANY (US) 1993-11-30 US claimed
EP-0557350-A1 ASSAY FOR GLYCATED BLOOD PROTEINS. AXIS RESEARCH (NO) 1993-09-01 EP claimed
EP-0531933-A2 Quantitative determination of liquids, pure or complexed with other components CANON KABUSHIKI KAISHA (JP) 1993-03-17 EP claimed
WO-1992008984-A1 ASSAY FOR GLYCATED BLOOD PROTEINS AXIS RESEARCH AS (NO) 1992-05-29 WO claimed
US-4839295-A Measurement of protein using bicinchoninic acid PIERCE CHEMICAL COMPANY (US) 1989-06-13 US claimed
US-4072627-A AVOIDANCE OF PROTEIN INTERFERENCE PIERCE CHEMICAL COMPANY (US) 1978-02-07 US claimed