Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.80 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.80 |
| ▸ | NPC1 | O15118 | 1/20 | 0.78 |
| ▸ | RAB9A | P51151 | 1/20 | 0.78 |
| ▸ | DHODH | Q02127 | 4/20 | 0.75 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | GLA | P06280 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.67 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.67 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29359819 | 0.98 | KDM4E (0.83) | KDM4ELMNASMN1; SMN2PDE10ANPC1 | |
| SCHEMBL18746 | 0.98 | KDM4E (0.83) | KDM4ELMNASMN1; SMN2PDE10ANPC1 | |
| SCHEMBL374558 | 0.96 | KDM4E (0.80) | KDM4ELMNASMN1; SMN2PDE10ANPC1 | |
| SCHEMBL30595092 | 0.96 | KDM4E (0.80) | KDM4ELMNASMN1; SMN2PDE10ANPC1 | |
| SCHEMBL374556 | 0.96 | KDM4E (0.80) | KDM4ELMNASMN1; SMN2PDE10ANPC1 | |
| SCHEMBL7962360 | 0.96 | KDM4E (0.80) | KDM4ELMNASMN1; SMN2PDE10ANPC1 | |
| SCHEMBL14518624 | 0.91 | NPC1 (0.77) | KDM4ELMNASMN1; SMN2PDE10ANPC1 | |
| SCHEMBL12131245 | 0.90 | KDM4E (0.71) | KDM4ELMNASMN1; SMN2PDE10ANPC1 | |
| Cinchophen SCHEMBL7588217 | 0.89 | KDM4E (1.00) | KDM4ELMNASMN1; SMN2PDE10ANPC1 | |
| Cinchophen SCHEMBL25519 | 0.89 | KDM4E (1.00) | KDM4ELMNASMN1; SMN2PDE10ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426191-A1 | Process for the homogenous hydrogenation of (poly)unsaturated hydrocarbons | Cognis IP Management GmbH (DE) | 2012-03-07 | — | — | EP | claimed |
| WO-2012016849-A1 | PROCESS FOR THE HOMOGENEOUS HYDROGENATION OF (POLY)UNSATURATED HYDROCARBONS | COGNIS IP MANAGEMENT GMBH (DE) | 2012-02-09 | — | — | WO | claimed |
| EP-2426191-A1 | Process for the homogenous hydrogenation of (poly)unsaturated hydrocarbons | Cognis IP Management GmbH (DE) | 2012-03-07 | — | — | EP | disclosed |
| WO-2012016849-A1 | PROCESS FOR THE HOMOGENEOUS HYDROGENATION OF (POLY)UNSATURATED HYDROCARBONS | COGNIS IP MANAGEMENT GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |
| US-6187928-B1 | TREATING FUNGAL DISEASES | THE ROCKEFELLER UNIVERSITY | 2001-02-13 | — | — | US | disclosed |
| US-6087510-A | Method of use of imidazolium cations | THE ROCKEFELLER UNIVERSITY (US) | 2000-07-11 | — | — | US | disclosed |
| US-5969150-A | FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES | THE ROCKEFELLER UNIVERSITY (US) | 1999-10-19 | — | — | US | disclosed |
| US-5874587-A | FLUORESCENCE | THE ROCKEFELLER UNIVERSITY (US) | 1999-02-23 | — | — | US | disclosed |