SCHEMBL374558

SCHEMBL374558

O=C(O)c1cc(-c2cc(C(=O)O)c3ccccc3n2)nc2ccccc12.[Na].[Na]

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.80
LMNA P02545 2/20 0.80
SMN1; SMN2 Q16637 2/20 0.80
PDE10A Q9Y233 1/20 0.80
NPC1 O15118 1/20 0.78
RAB9A P51151 1/20 0.78
DHODH Q02127 4/20 0.75
MEN1 O00255 3/20 0.71
KMT2A Q03164 3/20 0.71
POLB P06746 2/20 0.71
ALDH1A1 P00352 2/20 0.67
GLA P06280 2/20 0.67
GAA P10253 2/20 0.67
AKR1C3 P42330 1/20 0.67
AKR1C2 P52895 1/20 0.67
AKR1C1 Q04828 1/20 0.67
ESR1 P03372 1/20 0.67
TP53 P04637 1/20 0.67
HPGD P15428 1/20 0.67
MAPK1 P28482 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30595092 1.00 KDM4E (0.80) KDM4ELMNASMN1; SMN2PDE10ANPC1
SCHEMBL29359819 0.98 KDM4E (0.83) KDM4ELMNASMN1; SMN2PDE10ANPC1
SCHEMBL18746 0.98 KDM4E (0.83) KDM4ELMNASMN1; SMN2PDE10ANPC1
SCHEMBL7962360 0.96 KDM4E (0.80) KDM4ELMNASMN1; SMN2PDE10ANPC1
Potassium SCHEMBL93448 0.96 KDM4E (0.80) KDM4ELMNASMN1; SMN2PDE10ANPC1
SCHEMBL374556 0.96 KDM4E (0.80) KDM4ELMNASMN1; SMN2PDE10ANPC1
SCHEMBL14518624 0.91 NPC1 (0.77) KDM4ELMNASMN1; SMN2PDE10ANPC1
SCHEMBL12131245 0.90 KDM4E (0.71) KDM4ELMNASMN1; SMN2PDE10ANPC1
Cinchophen SCHEMBL7588217 0.89 KDM4E (1.00) KDM4ELMNASMN1; SMN2PDE10ANPC1
Cinchophen SCHEMBL25519 0.89 KDM4E (1.00) KDM4ELMNASMN1; SMN2PDE10ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119409631-A 2,2 '-Biquinoline-4, 4' -dicarboxylic acid amino acid derivative, and preparation method and application thereof 武汉大学人民医院(湖北省人民医院) 2025-02-11 CN claimed
CN-118374846-B Cyanide-free gold electroplating solution suitable for nickel-gold structure process 深圳创智芯联科技股份有限公司 2024-08-30 CN claimed
CN-118311027-B Kit and method for detecting alkaline washing effect of dairy production line 内蒙古大学 2024-08-27 CN claimed
CN-118546169-A Preparation method of silicone ether compound 五邑大学 2024-08-27 CN claimed
CN-118374846-A Cyanide-free gold electroplating solution suitable for nickel-gold structure process 深圳创智芯联科技股份有限公司 2024-07-23 CN claimed
CN-118311027-A Kit and method for detecting alkaline washing effect of dairy production line 内蒙古大学 2024-07-09 CN claimed
EP-1458787-B1 PROCESS FOR THE PRODUCTION OF BRANCHED MELT POLYCARBONATE BY LATE ADDITION OF FRIES-INDUCING CATALYST SABIC INNOVATIVE PLASTICS IP (NL) 2009-05-13 EP claimed
EP-1458787-A1 PROCESS FOR THE PRODUCTION OF BRANCHED MELT POLYCARBONATE BY LATE ADDITION OF FRIES-INDUCING CATALYST GENERAL ELECTRIC COMPANY (US) 2004-09-22 EP claimed
WO-2003057758-A1 PROCESS FOR THE PRODUCTION OF BRANCHED MELT POLYCARBONATE BY LATE ADDITION OF FRIES-INDUCING CATALYST GENERAL ELECTRIC COMPANY (US) 2003-07-17 WO claimed
US-6504002-B1 Melt strength GENERAL ELECTRIC COMPANY 2003-01-07 US claimed
CN-119569652-A 2,2 '-Biquinoline-4, 4' -dicarboxylic acid aliphatic amino acid derivative, preparation and application thereof 武汉大学人民医院(湖北省人民医院) 2025-03-07 CN disclosed
CN-119409631-A 2,2 '-Biquinoline-4, 4' -dicarboxylic acid amino acid derivative, and preparation method and application thereof 武汉大学人民医院(湖北省人民医院) 2025-02-11 CN disclosed
CN-119350977-A Front polishing additive suitable for BC battery and application method thereof 嘉兴市小辰光伏科技有限公司 2025-01-24 CN disclosed
CN-119350977-A Front polishing additive suitable for BC battery and application method thereof 嘉兴市小辰光伏科技有限公司 2025-01-24 CN disclosed
CN-118374846-B Cyanide-free gold electroplating solution suitable for nickel-gold structure process 深圳创智芯联科技股份有限公司 2024-08-30 CN disclosed
US-6087510-A Method of use of imidazolium cations THE ROCKEFELLER UNIVERSITY (US) 2000-07-11 US disclosed
US-5969150-A FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES THE ROCKEFELLER UNIVERSITY (US) 1999-10-19 US disclosed
US-5874587-A FLUORESCENCE THE ROCKEFELLER UNIVERSITY (US) 1999-02-23 US disclosed
EP-0763512-A1 AIR BAG GAS GENERATING AGENT OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-03-19 EP disclosed
US-5516700-A Automated urinalysis method CHIMERA RESEARCH AND CHEMICAL, INC. (US) 1996-05-14 US disclosed