Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1870034 | 0.89 | TLR7 (0.53) | KMT2ATLR7KDM4EABL1RIN1 | |
| SCHEMBL1871071 | 0.77 | PTGES (0.45) | KMT2AALDH1A1HPGDTLR7TSHR | |
| SCHEMBL1882183 | 0.76 | TLR7 (0.42) | KMT2AALDH1A1HPGDTLR7TSHR | |
| SCHEMBL1882180 | 0.76 | TLR7 (0.42) | KMT2AALDH1A1HPGDTLR7TSHR | |
| SCHEMBL1874349 | 0.73 | TLR7 (0.54) | TLR7 | |
| SCHEMBL1870397 | 0.72 | TLR7 (0.70) | TLR7 | |
| SCHEMBL1869091 | 0.71 | TLR7 (0.57) | TLR7 | |
| SCHEMBL3951639 | 0.69 | TLR7 (0.53) | TLR7 | |
| SCHEMBL12667653 | 0.69 | TLR7 (0.48) | ALDH1A1MAPTTLR7TP53 | |
| SCHEMBL1882626 | 0.69 | TLR7 (0.45) | KMT2AALDH1A1HPGDTLR7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011057148-A1 | COMPOUNDS AND COMPOSITIONS AS TLR-7 ACTIVITY MODULATORS | IRM LLC (BM) | 2011-05-12 | — | — | WO | disclosed |
| WO-2011057148-A1 | COMPOUNDS AND COMPOSITIONS AS TLR-7 ACTIVITY MODULATORS | IRM LLC (BM) | 2011-05-12 | — | — | WO | disclosed |