Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1882180 | 1.00 | TLR7 (0.42) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1877586 | 0.89 | TLR7 (0.53) | TLR7 | |
| SCHEMBL1877583 | 0.89 | TLR7 (0.53) | TLR7 | |
| SCHEMBL1871071 | 0.79 | PTGES (0.45) | TLR7PTGESTDP1FGFR1FGFR3 | |
| SCHEMBL1874671 | 0.76 | KMT2A (0.51) | TLR7KDM4EHPGDMEN1TSHR | |
| SCHEMBL1882626 | 0.69 | TLR7 (0.45) | TLR7PTGESADORA3PNPKDM4E | |
| SCHEMBL1870397 | 0.68 | TLR7 (0.70) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1869091 | 0.67 | TLR7 (0.57) | TLR7 | |
| SCHEMBL1881384 | 0.67 | TLR7 (0.58) | TLR7PTGESPNPKDM4EHPGD | |
| SCHEMBL1870034 | 0.67 | TLR7 (0.53) | TLR7KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011057148-A1 | COMPOUNDS AND COMPOSITIONS AS TLR-7 ACTIVITY MODULATORS | IRM LLC (BM) | 2011-05-12 | — | — | WO | disclosed |