Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | TTR | P02766 | 3/20 | 0.44 |
| ▸ | ALB | P02768 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.44 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.44 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16386398 | 1.00 | APP (0.47) | APPBCHEACHEPTGS2TTR | |
| SCHEMBL12801660 | 0.94 | APP (0.49) | APPBCHEACHEPTGS2TTR | |
| SCHEMBL16386151 | 0.79 | MT-CO2 (0.43) | PTGS2TTRPTGS1MT-CO2ADRA1A | |
| SCHEMBL16382953 | 0.74 | ALB (0.47) | ALBLMNAHIF1A | |
| SCHEMBL11200912 | 0.73 | CA12 (0.59) | APPBCHEACHEPTGS2TTR | |
| SCHEMBL12801807 | 0.72 | MT-CO2 (0.48) | PTGS2TTRPTGS1MT-CO2ADRA1A | |
| SCHEMBL18752850 | 0.72 | RXFP1 (0.45) | ADRA1ATRPV1CYP2C9LMNA | |
| SCHEMBL16382949 | 0.71 | GLI1 (0.47) | PTGS2PTGS1CXCL8CXCR1SLC22A6 | |
| SCHEMBL16382963 | 0.71 | AKR1C3 (0.55) | PTGS1AKR1C3 | |
| SCHEMBL25948151 | 0.70 | PTGS2 (0.63) | APPBCHEACHEPTGS2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940841-B9 | COMPOUNDS COMPRISING A BIOLOGICAL TARGET RECOGNIZING PART, COUPLED TO A SIGNAL PART CAPABLE OF COMPLEXING GALLIUM | GUERBET SA (FR) | 2017-04-19 | — | — | EP | disclosed |