Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 11/20 | 0.45 |
| ▸ | YAP1 | P46937 | 1/20 | 0.44 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.44 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12801456 | 0.95 | RXFP1 (0.50) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL18752846 | 0.90 | LMNA (0.51) | RXFP1TEAD4MAPTPOLBLMNA | |
| SCHEMBL12801457 | 0.84 | LMNA (0.54) | RXFP1TEAD4MAPTPOLBLMNA | |
| SCHEMBL16386151 | 0.82 | MT-CO2 (0.43) | MAPTADRA1ALMNACYP1A2CYP2C9 | |
| SCHEMBL12801807 | 0.75 | MT-CO2 (0.48) | MAPTADRA1ALMNACYP1A2CYP2C9 | |
| SCHEMBL18752851 | 0.72 | RXFP1 (0.54) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL12606017 | 0.72 | RXFP1 (0.67) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL16386398 | 0.72 | APP (0.47) | TRPV1ADRA1ALMNACYP2C9 | |
| SCHEMBL18752947 | 0.72 | APP (0.47) | TRPV1ADRA1ALMNACYP2C9 | |
| SCHEMBL13929951 | 0.70 | RXFP1 (0.64) | RXFP1YAP1TEAD4TEAD2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940841-B9 | COMPOUNDS COMPRISING A BIOLOGICAL TARGET RECOGNIZING PART, COUPLED TO A SIGNAL PART CAPABLE OF COMPLEXING GALLIUM | GUERBET SA (FR) | 2017-04-19 | — | — | EP | disclosed |