SCHEMBL18753602

SCHEMBL18753602

Cc1cc(Cl)ccc1SCCC=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK13 O15264 1/20 0.32
MAPK12 P53778 1/20 0.32
MAPK11 Q15759 1/20 0.32
MAPK14 Q16539 1/20 0.32
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 1/20 0.31
ITGB2 P05107 1/20 0.31
ICAM1 P05362 1/20 0.31
ITGAL P20701 1/20 0.31
MAPT P10636 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CCR2 P41597 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
SCN4A P35499 1/20 0.31
IRS1 P35568 1/20 0.30
GAB1 Q13480 1/20 0.30
TSHR P16473 1/20 0.30
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5544237 0.80 CA2 (0.38) TDP1ALDH1A1ITGB2ICAM1ITGAL
SCHEMBL18655384 0.78 DAO (0.33) ALDH1A1MAPTL3MBTL1
SCHEMBL16676455 0.76 CYP3A4 (0.40) CYP3A4MAPK1ALDH1A1MAPTCCR2
SCHEMBL9621322 0.75 RAB9A (0.43) TDP1MAPK1ALDH1A1MAPTTSHR
SCHEMBL5824516 0.75 CA2 (0.47) CYP3A4ALDH1A1MAPTCCR2MEN1
SCHEMBL11537655 0.73 CYP3A4 (0.38) TDP1CYP3A4MAPK13MAPK12MAPK11
SCHEMBL10778996 0.71 ALDH1A1 (0.54) CYP3A4ALDH1A1MAPTNPSR1TSHR
SCHEMBL18753526 0.71 TSHR (0.35) TDP1CYP3A4MAPK1TSHRHTR2A
SCHEMBL5542119 0.71 KDM4E (0.47) TDP1CYP3A4ALDH1A1MAPTL3MBTL1
SCHEMBL9476344 0.69 CYP3A4 (0.48) CYP3A4MAPK13MAPK12MAPK11MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2192163-B1 Ink composition and inkjet recording method FUJIFILM CORP (JP) 2017-04-19 EP disclosed