Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900397 | 0.79 | KMT2A (0.41) | SMN1; SMN2MAPTALDH1A1LMNARAB9A | |
| SCHEMBL12341497 | 0.70 | NOS3 (0.41) | MAPTGAAALDH1A1PKMMAPK1 | |
| SCHEMBL353805 | 0.70 | PDK2 (0.43) | SMN1; SMN2MAPTBAZ2BGAAALDH1A1 | |
| SCHEMBL8568255 | 0.69 | HDAC8 (0.45) | SMN1; SMN2MAPTBAZ2BALDH1A1HPGD | |
| SCHEMBL899803 | 0.68 | NCF1 (0.46) | HPGDNPSR1 | |
| SCHEMBL26906303 | 0.68 | MEN1 (0.46) | SMN1; SMN2BAZ2BALDH1A1MAPK1POLB | |
| SCHEMBL29827115 | 0.68 | MEN1 (0.46) | SMN1; SMN2BAZ2BALDH1A1MAPK1POLB | |
| SCHEMBL23889492 | 0.67 | NOS3 (0.39) | SMN1; SMN2MAPTGAAALDH1A1NOS3 | |
| SCHEMBL30632136 | 0.67 | ALDH1A1 (0.47) | SMN1; SMN2GAAALDH1A1HPGDLMNA | |
| SCHEMBL361910 | 0.66 | POLB (0.43) | MAPTGAAALDH1A1HPGDSPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3036235-B1 | NEW BIS-AMIDO PYRIDINES | BOEHRINGER INGELHEIM INT (DE) | 2017-04-19 | — | — | EP | disclosed |
| EP-3036228-B1 | NEW 6-ALKYNYL PYRIDINE COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2017-04-19 | — | — | EP | disclosed |