Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.51 |
| ▸ | DRD2 | P14416 | 6/20 | 0.51 |
| ▸ | HTR7 | P34969 | 6/20 | 0.51 |
| ▸ | DRD3 | P35462 | 6/20 | 0.51 |
| ▸ | HTR2B | P41595 | 6/20 | 0.51 |
| ▸ | HTR2A | P28223 | 5/20 | 0.51 |
| ▸ | HRH1 | P35367 | 5/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.48 |
| ▸ | PREP | P48147 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18755215 | 0.92 | PREP (0.51) | HTR1ADRD2HTR7DRD3HTR2B | |
| SCHEMBL5243620 | 0.80 | ACE (0.46) | HTR1ADRD2HTR7DRD3HTR2B | |
| SCHEMBL17559354 | 0.80 | ACE (0.46) | HTR1ADRD2HTR7DRD3HTR2B | |
| SCHEMBL3898933 | 0.80 | ACE (0.46) | HTR1ADRD2HTR7DRD3HTR2B | |
| SCHEMBL18755255 | 0.80 | HTR1A (0.54) | HTR1ADRD2HTR7DRD3HTR2B | |
| SCHEMBL23541884 | 0.76 | PREP (0.48) | HTR1ADRD2HTR7DRD3HTR2B | |
| SCHEMBL19927286 | 0.76 | POLB (0.55) | HTR1ADRD2HTR7DRD3HTR2B | |
| SCHEMBL19927287 | 0.76 | POLB (0.55) | HTR1ADRD2HTR7DRD3HTR2B | |
| SCHEMBL30377746 | 0.74 | CXCR3 (0.54) | HTR1AHTR7HTR2ACXCR3 | |
| SCHEMBL19931877 | 0.74 | PREP (0.53) | HTR1ADRD2HTR7DRD3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156398-A1 | AGONISTS OF THE CHEMOKINE RECEPTOR CXCR3 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2017-04-19 | — | — | EP | disclosed |