Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.52 |
| ▸ | PNMT | P11086 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2045883 | 0.80 | IDO1 (0.52) | IDO1PNMTTAAR1PKMLMNA | |
| SCHEMBL5251791 | 0.73 | GABRA1 (0.41) | LMNACYP2D6 | |
| SCHEMBL31736936 | 0.73 | TAAR1 (0.46) | IDO1TAAR1LMNATSHRCYP1A2 | |
| SCHEMBL809287 | 0.73 | TAAR1 (0.46) | TAAR1LMNATSHRCHRM2 | |
| SCHEMBL2047813 | 0.73 | TAAR1 (0.48) | IDO1TAAR1PKMLMNAAOC3 | |
| SCHEMBL672407 | 0.73 | IDO1 (0.62) | IDO1PNMTTAAR1PKMLMNA | |
| SCHEMBL29519238 | 0.73 | IDO1 (0.62) | IDO1PNMTTAAR1PKMLMNA | |
| SCHEMBL6740216 | 0.73 | TAAR1 (0.71) | IDO1PNMTTAAR1PKMLMNA | |
| SCHEMBL4238179 | 0.72 | TAAR1 (0.46) | PNMTTAAR1LMNATSHRNPC1 | |
| SCHEMBL5047988 | 0.71 | TP53 (0.44) | IDO1LMNATSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590499-B | Continuous reaction device and synthesis method of prothioconazole intermediate | 泰州百力化学股份有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-110590499-A | Continuous reaction device and synthesis method of prothioconazole intermediate | 泰州百力化学股份有限公司 | 2019-12-20 | — | — | CN | claimed |
| US-7273948-B2 | Process of preparing esters and ethers of probucol and derivatives thereof | ATHEROGENICS, INC. (US) | 2007-09-25 | — | — | US | claimed |
| EP-1594824-A4 | PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF | ATHEROGENICS INC (US) | 2007-04-04 | — | — | EP | claimed |
| EP-1594824-A2 | PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF | Atherogenics, Inc. (US) | 2005-11-16 | — | — | EP | claimed |
| US-20040204485-A1 | Process of preparing esters and ethers of probucol and derivatives thereof | CRABTREE ACQUISITION CO, LLC | 2004-10-14 | — | — | US | claimed |
| WO-2004062622-A2 | PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF | ATHEROGENICS, INC. (US) | 2004-07-29 | — | — | WO | claimed |
| US-12559466-B2 | Process for preparation of intermediates | UPL LTD (IN) | 2026-02-24 | — | — | US | disclosed |
| CN-114773249-B | Compounds, pharmaceutical compositions and methods for treating inflammatory diseases | 艾匹克治疗公司 | 2024-08-16 | — | — | CN | disclosed |
| US-12049461-B2 | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections | GILEAD SCIENCES, INC. (US) | 2024-07-30 | — | — | US | disclosed |
| EP-4385329-A2 | IMPROVED PROCESS FOR PREPARATION OF INTERMEDIATES | UPL Ltd (IN) | 2024-06-19 | — | — | EP | disclosed |
| CN-110590499-B | Continuous reaction device and synthesis method of prothioconazole intermediate | 泰州百力化学股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-116375658-A | Preparation method of prothioconazole | 宁夏苏融达化工有限公司 | 2023-07-04 | — | — | CN | disclosed |
| EP-0011770-B1 | FLUORENYL-AZOLYLMETHYL-CARBINOLS, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND METHOD FOR PREPARING OF THESE MEDICAMENTS | BAYER AG (DE) | 1981-10-14 | — | — | EP | disclosed |
| EP-0005250-B1 | HYDROXYPROPYL IMIDAZOLES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | BAYER AG (DE) | 1981-08-12 | — | — | EP | disclosed |
| US-4246274-A | MICROBIOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-20 | — | — | US | disclosed |
| US-4239765-A | ANTIMYCOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-16 | — | — | US | disclosed |
| EP-0011768-A1 | Hydroxypropyl triazoles, process for their preparation and medicaments containing these compounds | BAYER AG (DE) | 1980-06-11 | — | — | EP | disclosed |
| EP-0011770-A1 | Fluorenyl-azolylmethyl-carbinols, process for their preparation, medicaments containing them and method for preparing of these medicaments | BAYER AG (DE) | 1980-06-11 | — | — | EP | disclosed |
| EP-0005250-A2 | Hydroxypropyl imidazoles, their preparation and medicaments containing them | BAYER AG (DE) | 1979-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559466-B2 | Process for preparation of intermediates | CBR1, POR, CYP2E1 | IDO1 321/4885PNMT 445/4885TAAR1 500/4885 |
| US-12049461-B2 | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections | NR3C1, NR3C2, NR4A1 | IDO1 1289/4885PNMT 2911/4885TAAR1 319/4885 |
| US-20040204485-A1 | Process of preparing esters and ethers of probucol and derivatives thereof | NR3C2, MGLL, GCG | IDO1 4697/4885PNMT 541/4885TAAR1 3193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.