Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 4/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.32 |
| ▸ | HTR3B | O95264 | 3/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29745137 | 0.93 | CHKA (0.39) | ADRA2CALDH1A1KDM4EGAAMAPT | |
| SCHEMBL29745254 | 0.81 | ACVR1 (0.33) | — | |
| SCHEMBL14627790 | 0.80 | — | — | |
| SCHEMBL29745318 | 0.79 | CHRNA7 (0.43) | ALDH1A1KDM4EGAAMAPTGFER | |
| Bromide SCHEMBL7295860 | 0.78 | — | — | |
| SCHEMBL29745135 | 0.76 | CYP2D6 (0.30) | — | |
| SCHEMBL16501134 | 0.75 | LMNA (0.38) | ADRA2CALDH1A1KDM4EGAAMAPT | |
| SCHEMBL18932506 | 0.75 | — | — | |
| SCHEMBL29745092 | 0.74 | ESR1 (0.31) | ADRA2CESR2HRH4 | |
| SCHEMBL752178 | 0.73 | ALDH1A1 (0.34) | ADRA2CALDH1A1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787136-A | Substituted benzimidazole carboxamides and their use in the treatment of medical disorders | 比亚尔R&D投资股份公司 | 2022-07-22 | — | — | CN | disclosed |
| WO-2022026892-A1 | PIPERIDIN-1- YL-N-PYRYDI NE-3-YL-2-OXOACET AM IDE DERIVATIVES USEFUL FOR THE TREATMENT OF MTAP-DEFICIENT AND/OR MT A-ACCUMULATING CANCERS | TANGO THERAPEUTICS, INC. (US) | 2022-02-03 | — | — | WO | disclosed |
| EP-3156410-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-04-19 | — | — | EP | disclosed |