Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525054 | 0.86 | FFAR4 (0.42) | TGFBR1HDAC11MEN1KMT2A | |
| SCHEMBL11675845 | 0.82 | ADH1B (0.46) | TGFBR1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL11747509 | 0.82 | ADH1B (0.46) | TGFBR1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL14219281 | 0.82 | ADH1B (0.46) | TGFBR1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL472265 | 0.82 | ADH1B (0.46) | TGFBR1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL27597202 | 0.81 | TAS1R3 (0.45) | TGFBR1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL472236 | 0.81 | TGFBR1 (0.43) | TGFBR1RXFP1MEN1KMT2AMLYCD | |
| SCHEMBL10410222 | 0.79 | TRPV1 (0.37) | TRPV1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4089048 | 0.78 | TGFBR1 (0.47) | TGFBR1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL29519156 | 0.77 | TGFBR1 (0.50) | TGFBR1RXFP1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156032-A1 | DENTAL CEMENT | Kuraray Noritake Dental Inc. (JP) | 2017-04-19 | — | — | EP | disclosed |