Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | DRD3 | P35462 | 3/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | NCF1 | P14598 | 2/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 3/20 | 0.40 |
| ▸ | HTR1B | P28222 | 3/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18756980 | 0.85 | KMT2A (0.43) | HTR1ANCF1EGFRMAPTMAPK1 | |
| SCHEMBL18756963 | 0.84 | AOC3 (0.38) | HTR1ADRD2DRD3DRD4HTR2A | |
| SCHEMBL671924 | 0.83 | AOC3 (0.38) | HTR1ADRD2DRD3DRD4HTR2A | |
| SCHEMBL12368809 | 0.83 | NCF1 (0.61) | HTR1ADRD2DRD3DRD4HTR2A | |
| SCHEMBL12526392 | 0.83 | MAPT (0.44) | ADRA2CLMNAMAPTMAPK1KMT2A | |
| SCHEMBL12524358 | 0.82 | KDM4E (0.51) | LMNAMAPTKMT2AALDH1A1AOC3 | |
| SCHEMBL12525722 | 0.82 | ALDH1A1 (0.55) | NCF1HTR6LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL10711290 | 0.81 | NCF1 (0.59) | HTR1ADRD2DRD3DRD4HTR2A | |
| SCHEMBL15000972 | 0.81 | ALDH1A1 (0.58) | LMNAMAPK1KMT2AALDH1A1AOC3 | |
| SCHEMBL18757009 | 0.81 | AOC3 (0.39) | HTR1ADRD2DRD3DRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002278-B1 | GUANIDINE COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-04-19 | — | — | EP | disclosed |