Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29476745 | 1.00 | KDM4E (0.49) | KDM4EMEN1ALDH1A1GAAMAPT | |
| Butyric Acid SCHEMBL28118436 | 0.89 | KDM4E (0.46) | KDM4EMEN1ALDH1A1GAAMAPT | |
| Ethyl Acetate SCHEMBL28118437 | 0.89 | KDM4E (0.55) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL25224390 | 0.87 | MEN1 (0.43) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL29834920 | 0.87 | MEN1 (0.43) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL28909964 | 0.86 | KDM4E (0.47) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL5612010 | 0.85 | KDM4E (0.40) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL27236981 | 0.85 | KMT2A (0.72) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL30834272 | 0.84 | KDM4E (0.54) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL5896639 | 0.84 | KDM4E (0.54) | KDM4EMEN1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806504-B | Asymmetric chiral ligand and preparation method thereof, prepared catalyst, synthesis method and application | 合肥工业大学 | 2024-04-16 | — | — | CN | claimed |
| US-11884639-B2 | Preparation method for high optical indoxacarb intermediate | SHANDONG JINGBO AGROCHEMICALS TECHNOLOGY CO., LTD. (CN) | 2024-01-30 | — | — | US | claimed |
| US-11639336-B2 | Preparation method for S-indoxacarb | SHANDONG JINGBO AGROCHEMICALS TECHNOLOGY CO., LTD. (CN) | 2023-05-02 | — | — | US | claimed |
| CN-115896188-A | Preparation method of high-purity (S) -5-chloro-2-methoxycarbonyl-2-hydroxy-1-indanone | 大连奇凯医药科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115807042-A | Preparation method of indoxacarb intermediate | 弈柯莱生物科技(上海)股份有限公司 | 2023-03-17 | — | — | CN | claimed |
| CN-115806504-A | Asymmetric chiral ligand, preparation method thereof, prepared catalyst, synthesis method and application | 合肥工业大学 | 2023-03-17 | — | — | CN | claimed |
| CN-114105972-B | Cinchonine derivative and application thereof in preparation of high-optical-purity indoxacarb intermediate | 安徽广信农化股份有限公司 | 2022-12-23 | — | — | CN | claimed |
| CN-111747850-B | Method for synthesizing 5-chloro-1-oxo-2, 3-dihydro-1H-indene-2-carboxylic acid methyl ester by one-pot method | 山东京博生物科技有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-112345663-B | Analysis method for content of 5-chloro-2-methoxycarbonyl-1-indanone ester | 京博农化科技有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-113277948-B | Preparation method for preparing high-content indoxacarb intermediate | 京博农化科技有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-114181080-A | Green preparation method of 5-chloro-2-methoxycarbonyl-2-hydroxy-1-indanone | 阜新睿光氟化学有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-114105972-A | Xinkening derivative and application thereof in preparation of high-optical-purity indoxacarb intermediate | 安徽广信农化股份有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-110511217-B | Catalyst for catalyzing synthesis of indoxacarb key intermediate and application thereof | 京博农化科技有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-113940356-A | Indoxacarb microemulsion and preparation method thereof | 安徽广信农化股份有限公司 | 2022-01-18 | — | — | CN | claimed |
| CN-113277948-A | Preparation method for preparing high-content indoxacarb intermediate | 京博农化科技有限公司 | 2021-08-20 | — | — | CN | claimed |
| CN-105969815-B | Biological preparation method of (S) -5-chloro-2, 3-dihydro-2-hydroxy-1-oxo-1H-indene-2-carboxylic acid methyl ester | 苏州汉酶生物技术有限公司 | 2021-02-26 | — | — | CN | claimed |
| CN-111747850-A | Method for synthesizing 5-chloro-1-oxo-2, 3-dihydro-1H-indene-2-carboxylic acid methyl ester by one-pot method | 山东京博生物科技有限公司 | 2020-10-09 | — | — | CN | claimed |
| CN-111116507-A | Synthetic process of indoxacarb | 江苏腾龙生物药业有限公司 | 2020-05-08 | — | — | CN | claimed |
| CN-106397198-A | Preparation method of 5-chloro-2,3-dihydro-2-hydroxy-1-oxo-1H-indene-2-carboxylic acid methyl ester | 京博农化科技股份有限公司 | 2017-02-15 | — | — | CN | claimed |
| CN-105969815-A | Biological preparation method of (S)-5-chloro-2,3-dihydro-2-hydroxy-1-oxo-1H-indene-2-carboxylic methyl ester | 苏州汉酶生物技术有限公司 | 2016-09-28 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11639336-B2 | Preparation method for S-indoxacarb | SQLE, HPD, TDO2 | KDM4E 2154/4885MEN1 3570/4885ALDH1A1 165/4885 |
| US-11884639-B2 | Preparation method for high optical indoxacarb intermediate | IDO2, IDO1, DUOX2 | KDM4E 907/4885MEN1 3471/4885ALDH1A1 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.