Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.45 |
| ▸ | BHMT | Q93088 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425046 | 0.91 | BHMT (0.48) | GPR84BHMTSLC22A6ACE2BLM | |
| SCHEMBL29991721 | 0.88 | GPR84 (0.50) | GPR84BHMTSLC22A6ACE2BLM | |
| SCHEMBL14360558 | 0.85 | BHMT (0.48) | GPR84BHMTSLC22A6ACE2BLM | |
| SCHEMBL5743247 | 0.82 | BLM (0.52) | GPR84BHMTACE2BLM | |
| SCHEMBL8569864 | 0.82 | BHMT (0.43) | GPR84BHMTSLC22A6ACE2BLM | |
| SCHEMBL30882121 | 0.82 | GPR84 (0.61) | GPR84SLC22A6ACE2MAPTALDH1A1 | |
| SCHEMBL1483353 | 0.82 | LMNA (0.50) | GPR84SLC22A6ALDH1A1 | |
| SCHEMBL15514456 | 0.82 | GPR84 (0.45) | GPR84BHMTACE2BLMMAPT | |
| SCHEMBL3315960 | 0.82 | BLM (0.52) | GPR84BHMTACE2BLM | |
| SCHEMBL544052 | 0.82 | GPR84 (0.61) | GPR84SLC22A6ACE2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105417-A1 | Drug Conjugates | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2011-05-05 | — | — | US | disclosed |
| WO-2009158633-A1 | DRUG CONJUGATES | CURATORS OF THE UNIVERSITY OF MISSOURI ON BEHALF OF THE UNIVERSITY OF MISSOURI-KANSAS CITY (US) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105417-A1 | Drug Conjugates | ABCB1, SLCO2B1, ABCG2 | GPR84 428/4885BHMT 2417/4885SLC22A6 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.