SCHEMBL187606

SCHEMBL187606

CC(Br)C(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
PGR P06401 1/20 0.52
ADRA2A P08913 1/20 0.52
ADRA2B P18089 1/20 0.52
HTR2A P28223 1/20 0.52
HRH1 P35367 1/20 0.52
KCNH2 Q12809 1/20 0.52
CES2 O00748 5/20 0.50
CES1 P23141 5/20 0.50
LMNA P02545 4/20 0.50
ALDH1A1 P00352 4/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.47
NPSR1 Q6W5P4 2/20 0.47
MAPT P10636 2/20 0.47
ATM Q13315 2/20 0.47
MDM2 Q00987 1/20 0.47
XBP1 P17861 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19695429 1.00 TDP1 (0.52) TDP1L3MBTL1PGRADRA2AADRA2B
SCHEMBL1928398 0.87 SMN1; SMN2 (0.57) L3MBTL1LMNAALDH1A1CYP1A2CYP2C9
SCHEMBL96304 0.83 TDP1 (0.54) TDP1L3MBTL1PGRADRA2AADRA2B
SCHEMBL28878824 0.82 ALDH1A1 (0.59) TDP1L3MBTL1PGRADRA2AADRA2B
SCHEMBL8995325 0.82 ALDH1A1 (0.45) TDP1L3MBTL1PGRADRA2AADRA2B
SCHEMBL11433567 0.82 PARP10 (0.55) ALDH1A1CYP1A2SMN1; SMN2MAPTNPC1
SCHEMBL5082420 0.82 PARP10 (0.58) TDP1L3MBTL1ALDH1A1SMN1; SMN2MAPT
SCHEMBL10832183 0.82 PGR (0.48) TDP1L3MBTL1PGRADRA2AADRA2B
SCHEMBL2026667 0.82 PGR (0.48) TDP1L3MBTL1PGRADRA2AADRA2B
SCHEMBL8995222 0.81 L3MBTL1 (0.51) L3MBTL1LMNAALDH1A1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 986 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036642-A Methyl pinonate thiazole hydrazone derivative and preparation method and application thereof 江西农业大学 2026-05-15 CN claimed
CN-116769741-B Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone 河北牧群生物科技有限公司 2024-06-18 CN claimed
CN-116769741-A Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone 河北牧群生物科技有限公司 2023-09-19 CN claimed
CN-113178602-A Preparation of ZIF-8/polyether-ether-ketone and ZIF-8@ GO/polyether-ether-ketone anion composite membrane 长春工业大学 2021-07-27 CN claimed
CN-108676016-A A kind of synthetic method of myrte base imidazo [2,1-b] [1,3,4] thiadiazole compound 广西大学 2018-10-19 CN claimed
CN-106442829-A Method of simultaneously detecting contents of fatty acid and active matter in fatty acyl neutral amino acid surfactant 广州天赐高新材料股份有限公司 2017-02-22 CN claimed
CN-101857887-A Method for preparing optically pure aryl alcohol with cell-free extracts of recombinant strains by catalytic asymmetric conversion UNIV JIANGNAN 2010-10-13 CN claimed
US-20060153929-A1 Use of solid phase synthesis to modify and to assemble nanoparticles INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2006-07-13 US claimed
WO-2005110955-A1 SUBSTITUTED ACETOPHENOME AS MS REAGENTS GE HEALTHCARE BIO-SCIENCES AB (SE) 2005-11-24 WO claimed
WO-1999051590-A1 SUBSTITUTED INDOLINONES AS KINASE INHIBITORS BOEHRINGER INGELHEIM PHARMA KG (DE) 1999-10-14 WO claimed
EP-0139590-B1 4-ETHYL-2-HYDROXY-3-METHYL-2-PHENYLMORPHOLINE AND ITS ADDITION SALTS LABORATOIRE L. LAFON Société anonyme dite: (FR) 1988-06-22 EP claimed
JP-62238233-A None JP disclosed
JP-59053436-A None JP disclosed
JP-4059874-A None JP disclosed
CN-122036642-A Methyl pinonate thiazole hydrazone derivative and preparation method and application thereof 江西农业大学 2026-05-15 CN disclosed
US-3988375-A HERBICIDES MONSANTO COMPANY (US) 1976-10-26 US disclosed
US-3982942-A MANGANESE CARBONYL CATALYST ICI UNITED STATES INC. (US) 1976-09-28 US disclosed
US-3971772-A ANTINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1976-07-27 US disclosed
US-3964896-A Oxadiazole benzoic acid derivatives as herbicides UNIROYAL, INC. (US) 1976-06-22 US disclosed
US-3946071-A HERBICIDES MONSANTO COMPANY (US) 1976-03-23 US disclosed