SCHEMBL1876502

SCHEMBL1876502

O=C=NC(F)(C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32
LMNA P02545 1/20 0.32
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32681740 0.90 THRB (0.32) THRBLMNACA2
SCHEMBL15668368 0.90 THRB (0.32) THRBLMNACA2
SCHEMBL17181224 0.90 THRB (0.32) THRBLMNACA2
SCHEMBL8644218 0.86 THRB (0.30) THRB
SCHEMBL2760846 0.77 LMNA (0.33) THRBLMNACA2
SCHEMBL2761448 0.77 LMNA (0.33) THRBLMNACA2
SCHEMBL2760870 0.77 LMNA (0.33) THRBLMNACA2
SCHEMBL9420810 0.77 LMNA (0.33) THRBLMNACA2
SCHEMBL10401110 0.77 LMNA (0.33) THRBLMNACA2
SCHEMBL28570433 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0871700-A2 NOVEL SYSTEM FOR MULTILAYER GROWTH OF ANCHORAGE-DEPENDENT CELLS THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1998-10-21 EP claimed
WO-1997000941-A2 NOVEL SYSTEM FOR MULTILAYER GROWTH OF ANCHORAGE-DEPENDENT CELLS UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1997-01-09 WO claimed
US-20130090260-A1 Multiplexed Assay Using Spectrally-Encoded Solid Support Matrices IRORI TECHNOLOGIES, INC. (US) 2013-04-11 US disclosed
US-20120238466-A1 Multiplexed Assay Using Encoded Solid Support Matrices IRORI TECHNOLOGIES, INC. (US) 2012-09-20 US disclosed
US-8219327-B2 Multiplexed assay using encoded solid support matrices IRORI TECHNOLOGIES, INC. (US) 2012-07-10 US disclosed
US-20110237459-A1 Multiplexed Assay Using Encoded Solid Support Matrices NEXUS BIOSYSTEMS, INC. (US) 2011-09-29 US disclosed
US-20110212857-A1 Multiplexed Assay Using Encoded Solid Support Matrices NEXUS BIOSYSTEMS, INC. (US) 2011-09-01 US disclosed
US-7935659-B2 Multiplexed assays using encoded solid supports NEXUS BIOSYSTEMS, INC. (US) 2011-05-03 US disclosed
US-20090226891-A2 ENCODED SOLID SUPPORTS FOR BIOLOGICAL PROCESSING AND ASSAYS USING SAME NEXUS BIOSYSTEMS, INC. (US) 2009-09-10 US disclosed
EP-1925320-A2 Luciferases, fluorescent proteins, nucleic acids encoding the luciferases and fluorescent proteins and the use thereof in diagnostics Prolume, Ltd. (US) 2008-05-28 EP disclosed
EP-1064360-B1 LUCIFERASES, GFP FLUORESCENT PROTEINS, THEIR NUCLEIC ACIDS AND THE USE THEREOF IN DIAGNOSTICS PROLUME LTD (US) 2008-03-05 EP disclosed
US-5268456-A Immobilizing a protein; bonding to ligand E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-12-07 US disclosed
US-5268307-A Dissolving a perfluoroisocyanate emulsifier with ligand or binder E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-12-07 US disclosed
US-5243037-A Compounds for medical diagnosis and biosensors E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-07 US disclosed
EP-0549665-A1 POLY(FLUOROALKYL) SUGAR REAGENTS AND THEIR USE FOR SURFACE MODIFICATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-07-07 EP disclosed
WO-1992005445-A1 POLY(FLUOROALKYL) SUGAR REAGENTS AND THEIR USE FOR SURFACE MODIFICATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-02 WO disclosed
US-5079155-A Bioaffinity chromatography E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-07 US disclosed
EP-0363052-B1 PROCESS FOR PREPARING SOLID PERFLUOROCARBON POLYMER SUPPORTS HAVING ATTACHED PERFLUOROCARBON-SUBSTITUTED LIGAND OR BINDER E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-02 EP disclosed
US-4954444-A Fluorinated isocyanate anchor E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-04 US disclosed
EP-0363052-A1 Process for preparing solid perfluorocarbon polymer supports having attached perfluorocarbon-substituted ligand or binder E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-04-11 EP disclosed