SCHEMBL2760846

SCHEMBL2760846

O=C=NC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.33
CA2 P00918 1/20 0.31
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2761448 1.00 LMNA (0.33) LMNATHRBCA2F2PRSS1
SCHEMBL9420810 1.00 LMNA (0.33) LMNATHRBCA2F2PRSS1
SCHEMBL10401110 1.00 LMNA (0.33) LMNATHRBCA2F2PRSS1
SCHEMBL2760870 1.00 LMNA (0.33) LMNATHRBCA2F2PRSS1
SCHEMBL21878439 0.97
SCHEMBL15412434 0.92
SCHEMBL15412787 0.92
SCHEMBL8644223 0.92
SCHEMBL28355676 0.92
SCHEMBL8688048 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8242312-B2 Urethane and urea fluorosurfactants E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-08-14 US disclosed
WO-2012064417-A1 URETHANE AND UREA FLUOROSURFACTANTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-18 WO disclosed
US-20120122999-A1 URETHANE AND UREA FLUOROSURFACTANTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-17 US disclosed
US-7842626-B2 Partially fluorinated compositions and surface active agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-11-30 US disclosed
US-20080113172-A1 Partially fluorinated compositions and surface active agents E. I. DU PONT DE NEMOURS AND COMPANY 2008-05-15 US disclosed
US-4980096-A Protective coatings; adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-12-25 US disclosed
US-4740600-A UNBLOCKING WITH ACTINIC RADIATION; PROTECTIVE COATING; THERMOPLASTIC RESIN MIXTURES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-04-26 US disclosed
US-4599273-A PROTECTIVE COATINGS, PRESSURE SENSITIVE ADHESIVES MINNESOTA MINING AND MANUFACTURING CO. (US) 1986-07-08 US disclosed
EP-0046083-B1 PHOTOLABILE BLOCKED SURFACTANTS AND COMPOSITIONS CONTAINING THE SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-10-16 EP disclosed
US-4478967-A Photolabile blocked surfactants and compositions containing the same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-10-23 US disclosed
EP-0046083-A2 Photolabile blocked surfactants and compositions containing the same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-02-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080113172-A1 Partially fluorinated compositions and surface active agents FLNB, FLNA, FSCN1 LMNA 1129/4885THRB 3891/4885CA2 4039/4885
US-20120122999-A1 URETHANE AND UREA FLUOROSURFACTANTS QSOX1, SRM, AFF1 LMNA 2753/4885THRB 3588/4885CA2 3607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.