Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975163 | 0.89 | MAPT (0.51) | ALOX5LMNAKDM4EHDAC2HDAC8 | |
| SCHEMBL10437094 | 0.85 | ALOX5 (0.50) | ALOX5ALDH1A1TDP1L3MBTL1KEAP1 | |
| SCHEMBL13651467 | 0.85 | ALOX5 (0.50) | ALOX5ALDH1A1TDP1L3MBTL1KEAP1 | |
| SCHEMBL11389460 | 0.84 | F2RL1 (0.45) | ALDH1A1KDM4EFFAR1F2RL1POLB | |
| SCHEMBL758293 | 0.83 | TSHR (0.47) | ALDH1A1TDP1L3MBTL1RAB9ALMNA | |
| SCHEMBL8060407 | 0.82 | TAAR1 (0.42) | ALOX5FFAR1 | |
| SCHEMBL11396194 | 0.82 | FFAR1 (0.45) | ALDH1A1NPC1RAB9AFFAR1POLB | |
| SCHEMBL10015891 | 0.81 | KEAP1 (0.59) | ALOX5ALDH1A1TDP1L3MBTL1KEAP1 | |
| SCHEMBL9228714 | 0.80 | FFAR1 (0.44) | FFAR1F2RL1HDAC8 | |
| SCHEMBL11393286 | 0.79 | ACP3 (0.49) | ALOX5TDP1KDM4EFFAR1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947724-A | Synthesis method of latanoprost | 广州楷石医药有限公司 | 2023-10-27 | — | — | CN | claimed |
| EP-1721894-A1 | Process for the synthesis of prostaglandin derivatives | Technopharma S.A. (IT) | 2006-11-15 | — | — | EP | claimed |
| CN-116947724-A | Synthesis method of latanoprost | 广州楷石医药有限公司 | 2023-10-27 | — | — | CN | disclosed |
| US-20220169600-A1 | METHOD FOR PRODUCING PKROSTAGLANDIN | KYOWA PHARMA CHEMICAL CO., LTD. (JP) | 2022-06-02 | — | — | US | disclosed |
| EP-3950672-A1 | METHOD FOR PRODUCING PKROSTAGLANDIN | Kyowa Pharma Chemical Co., Ltd. (JP) | 2022-02-09 | — | — | EP | disclosed |
| CN-113557227-A | Method for producing prostaglandin | 协和医药化工股份有限公司 | 2021-10-26 | — | — | CN | disclosed |
| WO-2021070658-A1 | METHOD FOR PRODUCING CYCLOPENTANE COMPOUND, METHOD FOR PRODUCING LACTONE COMPOUND, METHOD FOR PRODUCING DIOL COMPOUND, AND COMPOUND | 国立大学法人東北大学 | 2021-04-15 | — | — | WO | disclosed |
| CN-111777538-A | Preparation method of bimatoprost | 南京栖云高活医药科技有限公司 | 2020-10-16 | — | — | CN | disclosed |
| WO-2020195437-A1 | METHOD FOR PRODUCING PKROSTAGLANDIN | 協和ファーマケミカル株式会社 | 2020-10-01 | — | — | WO | disclosed |
| EP-2495235-B1 | Process for the synthesis of prostaglandins and intermediates thereof | NEWCHEM S P A (IT) | 2015-08-05 | — | — | EP | disclosed |
| EP-2495235-B1 | Process for the synthesis of prostaglandins and intermediates thereof | NEWCHEM S P A (IT) | 2015-08-05 | — | — | EP | disclosed |
| US-4028419-A | PROSTAGLANDINS | THE UPJOIN COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-4026909-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1977-05-31 | — | — | US | disclosed |
| US-4018803-A | 13,14-Didehydro-PG3 compounds | THE UPJOHN COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |
| US-4013695-A | PROSTAGLANDINS, HYPOTENSIVES, OXYTOCICS, ANTISECRETORY AND ANTIULCER AGENTS, REPRODUCTION CONTROL | THE UPJOHN COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-3987087-A | ANTI-ULCER, NASAL PATENCY, WOUND HEALING, LABOR INDUCEMENT | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3987085-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3969396-A | 8β, 11β, 12α-PGE2 compounds | THE UPJOHN COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
| US-3931279-A | 5-Oxa prostaglandin F2.sub.α analogs | THE UPJOHN COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169600-A1 | METHOD FOR PRODUCING PKROSTAGLANDIN | PTGS1, PTGER1, RACK1 | ALOX5 220/4885ALDH1A1 1425/4885TDP1 4061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.