Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990438 | 0.86 | VNN1 (0.42) | MAOBMEN1KMT2AHCAR2 | |
| SCHEMBL11396194 | 0.83 | FFAR1 (0.45) | TAAR1FFAR1MEN1KMT2A | |
| SCHEMBL11393286 | 0.83 | ACP3 (0.49) | TAAR1FFAR1MAOBALOX5MEN1 | |
| SCHEMBL187684 | 0.82 | ALOX5 (0.51) | FFAR1ALOX5 | |
| SCHEMBL7340106 | 0.80 | TAAR1 (0.57) | TAAR1FFAR1CASP3CASP7 | |
| SCHEMBL7080205 | 0.78 | TAAR1 (0.49) | TAAR1FFAR1MAOBALOX5MEN1 | |
| SCHEMBL23901663 | 0.77 | IAPP (0.56) | TAAR1FFAR1MAOBCASP3CASP7 | |
| SCHEMBL901672 | 0.76 | TAAR1 (0.53) | TAAR1FFAR1MAOB | |
| SCHEMBL9681176 | 0.76 | ALOX5 (0.54) | ALOX5MEN1KMT2A | |
| SCHEMBL8959031 | 0.76 | IDO1 (0.46) | TAAR1MAOBMEN1KMT2AHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014991-A1 | PROSTAGLANDIN DERIVATIVES DEVOID OF SIDE-EFFECTS FOR THE TREATMENT OF GLAUCOMA | Pharmacia & Upjohn AB (SE) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999002165-A1 | PROSTAGLANDIN DERIVATIVES DEVOID OF SIDE-EFFECTS FOR THE TREATMENT OF GLAUCOMA | PHARMACIA & UPJOHN AB (SE) | 1999-01-21 | — | — | WO | disclosed |