Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18768399 | 0.89 | MEN1 (0.56) | AKR1C3 | |
| SCHEMBL18768576 | 0.89 | LMNA (0.47) | — | |
| SCHEMBL18768493 | 0.87 | AKR1C3 (0.46) | AKR1C3 | |
| SCHEMBL18768626 | 0.87 | MEN1 (0.46) | AKR1C3 | |
| SCHEMBL18768575 | 0.87 | — | — | |
| SCHEMBL18768434 | 0.87 | — | — | |
| SCHEMBL18768433 | 0.86 | HRH4 (0.57) | AKR1C3 | |
| SCHEMBL18768360 | 0.86 | AKR1C3 (0.46) | AKR1C3DRD2DRD4 | |
| SCHEMBL18768442 | 0.85 | PKM (0.39) | AKR1C3DRD2DRD4 | |
| SCHEMBL18768401 | 0.85 | ALDH1A1 (0.51) | DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066705-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | WO | disclosed |