Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | CCR1 | P32246 | 3/20 | 0.50 |
| ▸ | CCR5 | P51681 | 3/20 | 0.50 |
| ▸ | CCR8 | P51685 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434417 | 0.81 | KDM4E (0.50) | KDM4ELMNAMAPTHTTCCR1 | |
| SCHEMBL21686481 | 0.80 | PSMD14 (0.47) | KDM4ELMNAMAPTHTTCCR1 | |
| SCHEMBL17709420 | 0.79 | KDM4E (0.48) | KDM4ELMNAMAPTHTTCCR1 | |
| SCHEMBL17709421 | 0.79 | KDM4E (0.48) | KDM4ELMNAMAPTHTTCCR1 | |
| SCHEMBL29419886 | 0.77 | MMP2 (0.61) | KDM4ELMNAMAPTHTTCCR1 | |
| SCHEMBL16469239 | 0.77 | MMP2 (0.61) | KDM4ELMNAMAPTHTTCCR1 | |
| SCHEMBL11581594 | 0.76 | KDM4E (0.54) | KDM4ELMNAMAPTHTTCCR1 | |
| SCHEMBL8581634 | 0.76 | KDM4E (0.54) | KDM4ELMNAMAPTHTTCCR1 | |
| SCHEMBL11581590 | 0.76 | KDM4E (0.54) | KDM4ELMNAMAPTHTTCCR1 | |
| SCHEMBL21686716 | 0.73 | MMP2 (0.51) | KDM4ELMNAMAPTHTTCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362518-B1 | SENSOR DYES FOR REAL-TIME SENSING OF METAL IONS IN AQUEOUS ENVIRONMENTS | THE UWM RES FOUNDATION INC (US) | 2022-04-27 | — | — | EP | disclosed |
| WO-2017066672-A1 | SENSOR DYES FOR REAL-TIME SENSING OF METAL IONS IN AQUEOUS ENVIRONMENTS | UWM RESEARCH FOUNDATION, INC. (US) | 2017-04-20 | — | — | WO | disclosed |