Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | COMT | P21964 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | METAP2 | P50579 | 1/20 | 0.61 |
| ▸ | METAP1 | P53582 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 11/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29419886 | 1.00 | MMP2 (0.61) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL21686716 | 0.85 | MMP2 (0.51) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL18741239 | 0.84 | LMNA (0.50) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL18741240 | 0.84 | LMNA (0.50) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL21686788 | 0.81 | TSHR (0.50) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL21686717 | 0.81 | MAPT (0.63) | MMP2TSHRCHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL27989592 | 0.79 | TSHR (0.95) | MMP2TSHRCHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL12492889 | 0.77 | TSHR (0.91) | MMP2TSHRCHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL37189 | 0.77 | TSHR (1.00) | MMP2TSHRCHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL253313 | 0.77 | TSHR (1.00) | MMP2TSHRCHRM1COMTADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362518-A1 | SENSOR DYES FOR REAL-TIME SENSING OF METAL IONS IN AQUEOUS ENVIRONMENTS | The UWM Research Foundation, Inc (US) | 2018-08-22 | — | — | EP | disclosed |
| WO-2017066672-A1 | SENSOR DYES FOR REAL-TIME SENSING OF METAL IONS IN AQUEOUS ENVIRONMENTS | UWM RESEARCH FOUNDATION, INC. (US) | 2017-04-20 | — | — | WO | disclosed |
| US-20150050592-A1 | TONER FOR ELECTROSTATIC CHARGE IMAGE DEVELOPMENT, METHOD OF MANUFACTURING THE SAME, AND IMAGE FORMING METHOD | Konica Minolta, Inc. (JP) | 2015-02-19 | — | — | US | disclosed |