Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.60 |
| ▸ | FABP4 | P15090 | 1/20 | 0.60 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.60 |
| ▸ | CDK2 | P24941 | 1/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | CD40 | P25942 | 3/20 | 0.46 |
| ▸ | CD40LG | P29965 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | CHAT | P28329 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | FABP1 | P07148 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23178061 | 0.86 | TTR (0.64) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL18768617 | 0.83 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL27615953 | 0.80 | CA1 (0.46) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL6911279 | 0.79 | TTR (0.64) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL11759224 | 0.79 | TTR (0.59) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL27459951 | 0.79 | TTR (0.59) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL1742117 | 0.78 | TTR (0.59) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL21725437 | 0.77 | TTR (0.60) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL6214963 | 0.76 | TTR (0.68) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL26885009 | 0.76 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066672-A1 | SENSOR DYES FOR REAL-TIME SENSING OF METAL IONS IN AQUEOUS ENVIRONMENTS | UWM RESEARCH FOUNDATION, INC. (US) | 2017-04-20 | — | — | WO | disclosed |