Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.64 |
| ▸ | FABP4 | P15090 | 1/20 | 0.64 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.64 |
| ▸ | CDK2 | P24941 | 1/20 | 0.64 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.64 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | CD40 | P25942 | 3/20 | 0.45 |
| ▸ | CD40LG | P29965 | 3/20 | 0.45 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
| ▸ | CHAT | P28329 | 1/20 | 0.41 |
| ▸ | FABP1 | P07148 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | MPL | P40238 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATIC | P31939 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23178061 | 0.82 | TTR (0.64) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL1742117 | 0.80 | TTR (0.59) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL18769044 | 0.79 | TTR (0.60) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL21725437 | 0.79 | TTR (0.60) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL14511497 | 0.79 | TTR (0.46) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL43158 | 0.78 | FABP4 (1.00) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL27459951 | 0.78 | TTR (0.59) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL11759224 | 0.78 | TTR (0.59) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL29381891 | 0.78 | FABP4 (1.00) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL1786500 | 0.77 | FABP4 (0.97) | TTRFABP4CCNA2CDK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040038254-A1 | Compositions and methods for detecting nucleic acid methylation | THIEN, DOUGLAS Y. | 2004-02-26 | — | — | US | disclosed |
| EP-0063852-A2 | Energy absorbing particle quenching in light emitting competitive protein binding assays | SYVA COMPANY (US) | 1982-11-03 | — | — | EP | disclosed |