Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | FABP4 | P15090 | 1/20 | 0.59 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.59 |
| ▸ | CDK2 | P24941 | 1/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.59 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CD40 | P25942 | 3/20 | 0.54 |
| ▸ | CD40LG | P29965 | 3/20 | 0.54 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095224 | 0.86 | ALDH1A1 (0.50) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL10506952 | 0.85 | ALDH1A1 (0.54) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL26885009 | 0.84 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL23178061 | 0.81 | TTR (0.64) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL6242038 | 0.81 | CD40 (0.61) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL2342479 | 0.81 | ALDH1A1 (0.55) | CASP6ALDH1A1HPGDSLC40A1MAOA | |
| SCHEMBL30673688 | 0.81 | ALDH1A1 (0.55) | CASP6ALDH1A1HPGDSLC40A1MAOA | |
| SCHEMBL6363338 | 0.80 | LMNA (0.52) | TTRFABP4CCNA2CDK2MAPK14 | |
| Hydrochloric Acid SCHEMBL11760825 | 0.80 | ALDH1A1 (0.53) | CASP6ALDH1A1HPGDSLC40A1MAOA | |
| SCHEMBL7931655 | 0.79 | CASP6 (0.52) | TTRCASP6ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4036838-A | Process for the production of nitro derivatives of aromatic compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |