Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.30 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.30 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.30 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27659442 | 1.00 | CA12 (0.32) | CA12CA1CA2CA9ALDH1A1 | |
| Furan SCHEMBL27640919 | 0.87 | — | — | |
| SCHEMBL3722250 | 0.87 | CA12 (0.37) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL5074939 | 0.87 | CA12 (0.37) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL4958591 | 0.87 | CA12 (0.37) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL19861525 | 0.87 | CA12 (0.37) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL3722255 | 0.87 | CA12 (0.37) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL4733005 | 0.80 | ALDH1A1 (0.30) | ALDH1A1TSHRLMNATDP1GBA1 | |
| SCHEMBL4733008 | 0.80 | ALDH1A1 (0.30) | ALDH1A1TSHRLMNATDP1GBA1 | |
| SCHEMBL5485603 | 0.80 | GBA1 (0.34) | ALDH1A1TSHRLMNATDP1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3641810-A1 | HERPES SIMPLEX VIRUS VACCINE | Modernatx, Inc. (US) | 2020-04-29 | — | — | EP | disclosed |
| WO-2018200737-A1 | HERPES SIMPLEX VIRUS VACCINE | MODERNATX, INC. (US) | 2018-11-01 | — | — | WO | disclosed |
| EP-3364980-A1 | NUCLEIC ACID VACCINES FOR VARICELLA ZOSTER VIRUS (VZV) | ModernaTX, Inc. (US) | 2018-08-29 | — | — | EP | disclosed |
| EP-3364950-A1 | TROPICAL DISEASE VACCINES | ModernaTX, Inc. (US) | 2018-08-29 | — | — | EP | disclosed |
| WO-2017070601-A1 | NUCLEIC ACID VACCINES FOR VARICELLA ZOSTER VIRUS (VZV) | MODERNATX, INC. (US) | 2017-04-27 | — | — | WO | disclosed |
| WO-2017070624-A1 | TROPICAL DISEASE VACCINES | MODERNATX, INC. (US) | 2017-04-27 | — | — | WO | disclosed |