SCHEMBL5485603

SCHEMBL5485603

NC1O[C@H](CO)[C@@H](O)[C@@]1(N)O

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 1/20 0.34
GAA P10253 1/20 0.34
ALDH1A1 P00352 2/20 0.30
TSHR P16473 2/20 0.30
LMNA P02545 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18769795 0.80 CA12 (0.32) GBA1GAAALDH1A1TSHRLMNA
SCHEMBL27659442 0.80 CA12 (0.32) GBA1GAAALDH1A1TSHRLMNA
SCHEMBL4733008 0.78 ALDH1A1 (0.30) GBA1GAAALDH1A1TSHRLMNA
SCHEMBL4733005 0.78 ALDH1A1 (0.30) GBA1GAAALDH1A1TSHRLMNA
SCHEMBL21471446 0.71 PDE4D (0.33)
Hydrochloric Acid SCHEMBL11075082 0.70 MGAM (0.40) GAA
Furan SCHEMBL27640919 0.70
SCHEMBL27656472 0.68 GBA1 (0.38) GBA1GAA
SCHEMBL4958591 0.68 CA12 (0.37) GBA1GAAALDH1A1TSHRLMNA
SCHEMBL30274154 0.68 CA12 (0.37) GBA1GAAALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7255835-B2 Single pass attenuated total reflection fourier transform infrared microscopy apparatus and method for identifying protein secondary structure, surface charge and binding affinity NORTH CAROLINA STATE UNIVERSITY (US) 2007-08-14 US disclosed
WO-2003085422-A2 SINGLE PASS ATTENUATED TOTAL REFLECTION INFRARED ANALYSIS IDENTIFYING PROTEIN SECONDARY STRUCTURE, SURFACE CHARGE AND BINDING AFFINITY NORTH CAROLINA STATE UNIVERSITY (US) 2003-10-16 WO disclosed
US-20030157725-A1 Single pass attenuated total reflection fourier transform infrared microscopy apparatus and method for identifying protein secondary structure, surface charge and binding affinity NORTH CAROLINA STATE UNIVERSITY 2003-08-21 US disclosed