Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733005 | 1.00 | ALDH1A1 (0.30) | ALDH1A1TSHRLMNATDP1GBA1 | |
| SCHEMBL27659442 | 0.80 | CA12 (0.32) | ALDH1A1TSHRLMNATDP1GBA1 | |
| SCHEMBL18769795 | 0.80 | CA12 (0.32) | ALDH1A1TSHRLMNATDP1GBA1 | |
| SCHEMBL5485603 | 0.78 | GBA1 (0.34) | ALDH1A1TSHRLMNATDP1GBA1 | |
| SCHEMBL14998736 | 0.77 | ALDH1A1 (0.32) | ALDH1A1TSHRLMNATDP1GBA1 | |
| SCHEMBL7070891 | 0.76 | — | — | |
| SCHEMBL12496895 | 0.76 | — | — | |
| SCHEMBL7640916 | 0.74 | ADORA2A (0.38) | ALDH1A1TSHRLMNATDP1 | |
| SCHEMBL170812 | 0.74 | ADORA2A (0.38) | ALDH1A1TSHRLMNATDP1 | |
| SCHEMBL3995295 | 0.74 | ADORA2A (0.38) | ALDH1A1TSHRLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710182-B2 | Rapid glycopeptide optimization via neoglycosylation | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-04-29 | — | — | US | disclosed |
| US-20130030151-A1 | RAPID GLYCOPEPTIDE OPTIMIZATION VIA NEOGLYCOSYLATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-01-31 | — | — | US | disclosed |
| US-8236926-B2 | Chemoselectively ligating sugar moiety to alkoxylamine-containing vancomycin; for inhibiting growth of resistant Enterococci | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-08-07 | — | — | US | disclosed |
| WO-2008076483-A9 | RAPID VANCOMYCIN DERIVATIVE PREPARATION VIA NEOGLYCOSYLATION | WISCONSIN ALUMNI RES FOUND (US) | 2008-08-07 | — | — | WO | disclosed |
| WO-2008076483-A2 | RAPID VANCOMYCIN DERIVATIVE PREPARATION VIA NEOGLYCOSYLATION | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-06-26 | — | — | WO | disclosed |
| US-20080114157-A1 | RAPID GLYCOPEPTIDE OPTIMIZATION VIA NEOGLYCOSYLATION | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-05-15 | — | — | US | disclosed |