Phenazine

Phenazine

SCHEMBL18770795

c1ccc(-c2ccccc2)cc1.c1ccc2nc3ccccc3nc2c1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.73
▸ ALDH1A1 P00352 5/20 0.60
▸ NQO2 P16083 3/20 0.55
▸ KDM4E B2RXH2 4/20 0.54
▸ PKM P14618 1/20 0.54
▸ TDP1 Q9NUW8 3/20 0.52
▸ MEN1 O00255 3/20 0.52
▸ KMT2A Q03164 3/20 0.52
▸ GAA P10253 2/20 0.52
▸ L3MBTL1 Q9Y468 2/20 0.52
▸ LMNA P02545 1/20 0.52
▸ HPGD P15428 3/20 0.50
▸ GLA P06280 2/20 0.50
▸ MAOA P21397 2/20 0.50
▸ ACHE P22303 2/20 0.50
▸ HSD17B10 Q99714 2/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ CHRM2 P08172 1/20 0.50
▸ ADRA2A P08913 1/20 0.50
▸ ADORA3 P0DMS8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenazine SCHEMBL28253056 0.89 MAPT (0.92) MAPTALDH1A1NQO2KDM4ETDP1
Phenazine SCHEMBL182948 0.86 MAPT (0.85) MAPTALDH1A1NQO2KDM4ETDP1
Phenazine SCHEMBL27643128 0.86 MAPT (1.00) MAPTALDH1A1NQO2KDM4ETDP1
Phenazine SCHEMBL9049 0.86 MAPT (1.00) MAPTALDH1A1NQO2KDM4ETDP1
Phenazine SCHEMBL29356959 0.86 MAPT (1.00) MAPTALDH1A1NQO2KDM4ETDP1
SCHEMBL5157311 0.84 PIK3CA (0.58) MAPTALDH1A1NQO2KDM4ETDP1
SCHEMBL24590007 0.83 KDM4E (0.75) MAPTALDH1A1KDM4EPKMTDP1
Acridine SCHEMBL27748113 0.83 ALDH1A1 (0.79) MAPTALDH1A1NQO2KDM4ETDP1
SCHEMBL13726198 0.83 KDM4E (0.75) MAPTALDH1A1KDM4EPKMTDP1
Phenazine SCHEMBL20475326 0.82 MAPT (0.92) MAPTALDH1A1NQO2KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11692065-B2 Phenazine copolymers and uses thereof CORNELL UNIVERSITY (US) 2023-07-04 — — US disclosed
US-11345771-B2 Compositions and methods of promoting organic photocatalysis THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2022-05-31 — — US disclosed
US-20220153931-A1 PHENAZINE COPOLYMERS AND USES THEREOF CORNELL UNIVERSITY 2022-05-19 — — US disclosed
US-10975171-B2 Compositions and methods of promoting organic photocatalysis THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2021-04-13 — — US disclosed
WO-2020205796-A1 PHENAZINE COPOLYMERS AND USES THEREOF CORNELL UNIVERSITY (US) 2020-10-08 — — WO disclosed
US-20180237550-A1 COMPOSITIONS AND METHODS OF PROMOTING ORGANIC PHOTOCATALYSIS CHARGEPOINT INC. 2018-08-23 — — US disclosed
WO-2017070560-A1 COMPOSITIONS AND METHODS OF PROMOTING ORGANIC PHOTOCATALYSIS THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2017-04-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11345771-B2 Compositions and methods of promoting organic photocatalysis TYR, ALKBH2, CYBB MAPT 2591/4885ALDH1A1 1151/4885NQO2 486/4885
US-20180237550-A1 COMPOSITIONS AND METHODS OF PROMOTING ORGANIC PHOTOCATALYSIS TYR, ALKBH2, CYBB MAPT 2591/4885ALDH1A1 1151/4885NQO2 486/4885
US-10975171-B2 Compositions and methods of promoting organic photocatalysis TYR, ALKBH2, CYBB MAPT 2591/4885ALDH1A1 1151/4885NQO2 486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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