Acridine

Acridine

SCHEMBL18770814

C=C(C)C(=O)OC.c1ccc2nc3ccccc3cc2c1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
MAPT P10636 5/20 0.50
HPGD P15428 3/20 0.50
GLA P06280 2/20 0.50
ACHE P22303 1/20 0.50
KDM4E B2RXH2 6/20 0.41
KMT2A Q03164 3/20 0.41
RAB9A P51151 3/20 0.41
MEN1 O00255 2/20 0.41
NPC1 O15118 2/20 0.41
PABPC1 P11940 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TLR8 Q9NR97 1/20 0.40
TNNI3 P19429 1/20 0.40
TNNT2 P45379 1/20 0.40
TNNC1 P63316 1/20 0.40
RUNX1 Q01196 1/20 0.40
CBFB Q13951 1/20 0.40
GAA P10253 2/20 0.40
HTR3A P46098 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthracene SCHEMBL909619 0.88 ALDH1A1 (0.60) ALDH1A1MAPTHPGDKDM4EKMT2A
SCHEMBL28157624 0.86 ALDH1A1 (0.58) ALDH1A1MAPTHPGDKDM4EKMT2A
Naphthalene SCHEMBL4378459 0.84 ALDH1A1 (0.65) ALDH1A1MAPTKDM4EKMT2ARAB9A
Anthracene SCHEMBL27835058 0.83 ALDH1A1 (0.54) ALDH1A1MAPTHPGDGLAKDM4E
Acridine SCHEMBL27555574 0.82 ALDH1A1 (0.58) ALDH1A1MAPTHPGDGLAACHE
Methacrylic Acid SCHEMBL27818242 0.81 ALDH1A1 (0.52) ALDH1A1MAPTHPGDGLAKDM4E
SCHEMBL27609119 0.80 ELANE (0.41) ALDH1A1MAPTHPGDGLAACHE
Acridine SCHEMBL11500721 0.78 MAPT (0.68) ALDH1A1MAPTHPGDGLAACHE
SCHEMBL8968152 0.76 TLR8 (0.48) ALDH1A1MAPTHPGDKDM4EKMT2A
Pyrene SCHEMBL678886 0.75 ALDH1A1 (0.58) ALDH1A1MAPTHPGDKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11345771-B2 Compositions and methods of promoting organic photocatalysis THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2022-05-31 US disclosed
US-10975171-B2 Compositions and methods of promoting organic photocatalysis THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2021-04-13 US disclosed
US-20180237550-A1 COMPOSITIONS AND METHODS OF PROMOTING ORGANIC PHOTOCATALYSIS CHARGEPOINT INC. 2018-08-23 US disclosed
WO-2017070560-A1 COMPOSITIONS AND METHODS OF PROMOTING ORGANIC PHOTOCATALYSIS THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2017-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11345771-B2 Compositions and methods of promoting organic photocatalysis TYR, ALKBH2, CYBB ALDH1A1 1151/4885MAPT 2591/4885HPGD 1298/4885
US-20180237550-A1 COMPOSITIONS AND METHODS OF PROMOTING ORGANIC PHOTOCATALYSIS TYR, ALKBH2, CYBB ALDH1A1 1151/4885MAPT 2591/4885HPGD 1298/4885
US-10975171-B2 Compositions and methods of promoting organic photocatalysis TYR, ALKBH2, CYBB ALDH1A1 1151/4885MAPT 2591/4885HPGD 1298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.