Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567448 | 0.82 | TLR8 (0.53) | TLR8RAB9AMAPTSMN1; SMN2BTK | |
| SCHEMBL27609119 | 0.81 | ELANE (0.41) | TLR8RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6565258 | 0.81 | TLR8 (0.51) | TLR8RAB9AMAPTSMN1; SMN2BTK | |
| SCHEMBL12458543 | 0.77 | ELANE (0.54) | RAB9AMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL180365 | 0.77 | TLR8 (0.65) | TLR8RAB9AMAPTSMN1; SMN2BTK | |
| Acridine SCHEMBL18770814 | 0.76 | ALDH1A1 (0.50) | TLR8RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| Methacrylic Acid SCHEMBL8968158 | 0.76 | TLR8 (0.49) | TLR8RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27511729 | 0.75 | TLR8 (0.62) | TLR8RAB9AMAPTSMN1; SMN2BTK | |
| SCHEMBL2946336 | 0.74 | RAB9A (0.36) | TLR8RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8785457 | 0.74 | KDM4C (0.45) | TLR8RAB9AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482809-A | ELECTROGRAPHY, POLYMERS WITH METAL CHELATING GROUPS AND CROSSLINKING GROUPS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-01-09 | — | — | US | disclosed |