Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | ACLY | P53396 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1422230 | 0.99 | HTR6 (0.61) | HTR6HTR2CACLY | |
| SCHEMBL12659649 | 0.85 | HTR6 (0.59) | HTR6HTR2CACLY | |
| Hydrochloric Acid SCHEMBL1421918 | 0.84 | HTR6 (0.58) | HTR6HTR2CACLY | |
| SCHEMBL1421968 | 0.78 | HTR6 (0.67) | HTR6HTR2C | |
| SCHEMBL1422181 | 0.78 | HTR6 (0.61) | HTR6HTR2CACLY | |
| SCHEMBL3153057 | 0.77 | HTR6 (1.00) | HTR6HTR2C | |
| SCHEMBL3147527 | 0.77 | HTR6 (1.00) | HTR6HTR2C | |
| SCHEMBL3157092 | 0.76 | HTR6 (1.00) | HTR6HTR2C | |
| SCHEMBL12659652 | 0.76 | HTR6 (0.61) | HTR6HTR2C | |
| SCHEMBL1422178 | 0.76 | HTR6 (0.63) | HTR6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105555-A1 | SUBSTITUTED N-IMIDAZO[2,1-B]THIAZOLE-5-SULFONAMIDE DERIVATIVES AS 5-HT6 LIGANDS | LABORATORIOS DE. DR. ESTEVE, S.A. (ES) | 2011-05-05 | — | — | US | disclosed |
| US-20110105555-A1 | SUBSTITUTED N-IMIDAZO[2,1-B]THIAZOLE-5-SULFONAMIDE DERIVATIVES AS 5-HT6 LIGANDS | LABORATORIOS DE. DR. ESTEVE, S.A. (ES) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105555-A1 | SUBSTITUTED N-IMIDAZO[2,1-B]THIAZOLE-5-SULFONAMIDE DERIVATIVES AS 5-HT6 LIGANDS | HTR6, HTR1A, HTR5A | HTR6 1/4885HTR2C 7/4885ACLY 3936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.