SCHEMBL187727

SCHEMBL187727

CC(=O)c1cccnc1C(C)=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.55
ALDH1A1 P00352 4/20 0.55
ALOX15 P16050 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
MAPT P10636 2/20 0.55
CYP3A4 P08684 1/20 0.55
TSHR P16473 1/20 0.55
BLM P54132 1/20 0.55
AGER Q15109 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
TDP1 Q9NUW8 1/20 0.52
NAPRT Q6XQN6 2/20 0.44
LMNA P02545 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
P2RX7 Q99572 1/20 0.43
GAA P10253 1/20 0.41
MYC P01106 2/20 0.41
CYP1A2 P05177 1/20 0.40
PARP1 P09874 1/20 0.40
KDM4C Q9H3R0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3006650 0.88 KDM4E (0.74) KDM4EALDH1A1ALOX15L3MBTL1MAPT
SCHEMBL2584629 0.88 ALDH1A1 (0.74) KDM4EALDH1A1ALOX15L3MBTL1MAPT
SCHEMBL10654031 0.86 KDM4E (0.50) KDM4EALDH1A1ALOX15L3MBTL1MAPT
SCHEMBL2488255 0.86 PARP1 (0.53) KDM4EALDH1A1ALOX15L3MBTL1MAPT
Hydrochloric Acid SCHEMBL9630450 0.86 ALDH1A1 (0.71) KDM4EALDH1A1ALOX15L3MBTL1MAPT
Phenylhydrazine SCHEMBL27538152 0.83 PRKCI (0.50) KDM4EALDH1A1ALOX15L3MBTL1MAPT
SCHEMBL2800466 0.83 L3MBTL1 (0.54) KDM4EALDH1A1ALOX15L3MBTL1MAPT
SCHEMBL9632137 0.83 L3MBTL1 (0.58) KDM4EALDH1A1ALOX15L3MBTL1MAPT
SCHEMBL31515547 0.81 ALDH1A1 (0.50) KDM4EALDH1A1ALOX15L3MBTL1MAPT
SCHEMBL5929445 0.79 KDM4E (0.43) KDM4EALDH1A1ALOX15L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 609 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119842312-A Fluorine coating layer melt extruded on surface of polyimide film and preparation method thereof 东营林福商贸有限公司 2025-04-18 CN claimed
US-20250109158-A1 METHOD OF MANUFACTURE OF PENTAAZA MACROCYCLIC RING COMPLEX, INTERMEDIATES, AND PRODUCTS THEREOF BIOSSIL INC. (CA) 2025-04-03 US claimed
CN-119098128-A Self-regulating lipid photochemical reaction system with controllable reaction efficiency and analysis method 清谱科技(南通)有限公司 2024-12-10 CN claimed
CN-115236170-B Lipid component analysis system based on capillary electrophoresis, application thereof and analysis method of lipid component 清华大学 2024-11-26 CN claimed
WO-2024022312-A1 CAPILLARY ELECTROPHORESIS-BASED LIPIDOME ANALYSIS SYSTEM AS WELL AS USE THEREOF, AND LIPIDOME ANALYSIS METHOD 清华大学 2024-02-01 WO claimed
CN-115197127-B Ruthenium-containing complex, preparation method and application thereof 广州大学 2023-09-29 CN claimed
CN-110092744-B High-thermal-stability tertiary-butyl-containing asymmetric diimine pyridine complex, and preparation method and application thereof 中国科学院化学研究所 2023-04-18 CN claimed
CN-115236170-A Lipidosome analysis system based on capillary electrophoresis, application thereof and lipidosome analysis method 清华大学 2022-10-25 CN claimed
CN-115197127-A Ruthenium-containing complex, preparation method and application thereof 广州大学 2022-10-18 CN claimed
CN-111961090-B Asymmetric pyridine imine complex containing large steric hindrance substituent, preparation method and application thereof 中国科学院化学研究所 2021-10-22 CN claimed
CN-1202049-C Iron-based catalyst composition for ethylene oligomerization and application thereof CHINA NAT PETROLEUM CORP (CN) 2005-05-18 CN claimed
CN-1554676-A High molecular 复旦大学 2004-12-15 CN claimed
CN-1524884-A Synthesis method of supported late transition metal catalyst 中国石油天然气股份有限公司 2004-09-01 CN claimed
CN-1164534-C Iron catalyst and its prepn and application 中国科学院化学研究所 2004-09-01 CN claimed
EP-0828738-B1 PYRIDYL-THIAZOLES AND THEIR USE TO PROTECT PLANTS AGAINST INFECTIONS BY MICRO-ORGANISMS BAYER CROPSCIENCE AG (DE) 2003-12-17 EP claimed
WO-2003082824-A1 SYNTHESIS OF 2,6-DICARBONYLPYRIDINES BOULDER SCIENTIFIC COMPANY (US) 2003-10-09 WO claimed
CN-1408737-A Catalytic system for ethylene and acrylic ester copolymerization CHANGCHUN APPLIED CHEMISTRY (CN) 2003-04-09 CN claimed
CN-1398836-A Iron catalyst and its prepn and application CHINESE ACAD INST CHEMISTRY (CN) 2003-02-26 CN claimed
CN-1299376-A Polymerisation catalysts BP CHEM INT LTD (GB) 2001-06-13 CN claimed
EP-0204535-B1 N-FLUOROPYRIDINIUM SALT AND PROCESS FOR PREPARING SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-08-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250109158-A1 METHOD OF MANUFACTURE OF PENTAAZA MACROCYCLIC RING COMPLEX, INTERMEDIATES, AND PRODUCTS THEREOF PAICS, AADAC, RPS14 KDM4E 2397/4885ALDH1A1 2338/4885ALOX15 1783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.