Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | AGER | Q15109 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.40 |
| ▸ | MYC | P01106 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187727 | 0.86 | KDM4E (0.55) | KDM4EALDH1A1ALOX15L3MBTL1MAPT | |
| SCHEMBL890368 | 0.86 | KDM4E (0.55) | KDM4EALDH1A1ALOX15L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL28182285 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1ALOX15L3MBTL1MAPT | |
| SCHEMBL9275469 | 0.82 | KDM4E (0.74) | KDM4EALDH1A1ALOX15L3MBTL1MAPT | |
| SCHEMBL2584629 | 0.82 | ALDH1A1 (0.74) | KDM4EALDH1A1ALOX15L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL9630450 | 0.81 | ALDH1A1 (0.71) | KDM4EALDH1A1ALOX15L3MBTL1MAPT | |
| SCHEMBL2488255 | 0.81 | PARP1 (0.53) | KDM4EALDH1A1ALOX15L3MBTL1MAPT | |
| SCHEMBL2372518 | 0.80 | L3MBTL1 (0.57) | KDM4EALDH1A1ALOX15L3MBTL1MAPT | |
| SCHEMBL3263627 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1ALOX15L3MBTL1MAPT | |
| SCHEMBL2800466 | 0.78 | L3MBTL1 (0.54) | KDM4EALDH1A1ALOX15L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258182-A1 | Semicarbazones and thiosemicarbazones | SANDOZ AG (CH) | 1988-03-02 | — | — | EP | disclosed |