Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1884233 | 0.86 | — | — | |
| SCHEMBL1884231 | 0.86 | — | — | |
| SCHEMBL30894554 | 0.79 | — | — | |
| SCHEMBL4748246 | 0.79 | HCAR2 (0.36) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL4748143 | 0.79 | HCAR2 (0.36) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL8917913 | 0.76 | CTSL (0.40) | — | |
| SCHEMBL8917915 | 0.76 | CTSL (0.40) | — | |
| SCHEMBL1877802 | 0.74 | — | — | |
| SCHEMBL23247788 | 0.73 | GABRP (0.34) | — | |
| SCHEMBL8349584 | 0.71 | GRIK1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947738-B2 | Bicyclic γ-amino acid derivative | DAIICHI SANKYO COMPANY, LTD. (JP) | 2011-05-24 | — | — | US | disclosed |