SCHEMBL18779552

SCHEMBL18779552

c1ccc(-c2cccc(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5cc(-c7ccc8oc9ccccc9c8c7)ccc5n6-c5ccccc5)ccc43)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ATM Q13315 1/20 0.46
PLA2G2A P14555 4/20 0.42
PLA2G4A P47712 4/20 0.42
PLA2G10 O15496 1/20 0.40
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
NPC1 O15118 1/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TSPO P30536 1/20 0.37
PRKDC P78527 3/20 0.36
AHR P35869 1/20 0.35
PGR P06401 1/20 0.35
IL1R1 P14778 1/20 0.35
HDAC4 P56524 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18779523 1.00 KDM4E (0.46) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL21610878 1.00 KDM4E (0.46) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL14733868 1.00 KDM4E (0.46) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL20821701 0.99 KDM4E (0.45) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL20633260 0.99 KDM4E (0.45) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL20715024 0.99 KDM4E (0.47) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL17885294 0.99 KDM4E (0.47) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL12088796 0.99 KDM4E (0.47) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL11965555 0.99 KDM4E (0.47) KDM4EL3MBTL1ATMPLA2G2APLA2G4A
SCHEMBL22672361 0.99 KDM4E (0.44) KDM4EL3MBTL1ATMPLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917907-B2 Organic electroluminescent device ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-02-27 US disclosed
US-11917907-B2 Organic electroluminescent device ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-02-27 US disclosed
EP-4186898-A1 COMPOSITION FOR ORGANIC ELECTRONIC COMPOUNDS Merck Patent GmbH (DE) 2023-05-31 EP disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-11527728-B2 Organic electroluminescent compounds and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2022-12-13 US disclosed
US-20220102633-A1 ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2022-03-31 US disclosed
EP-3649213-B1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-06-23 EP disclosed
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-23 US disclosed
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-09 US disclosed
US-20170279056-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-09-28 US disclosed
US-20170279056-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-09-28 US disclosed
US-20170213968-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-07-27 US disclosed
US-20170213968-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-07-27 US disclosed
US-20170207396-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-07-20 US disclosed
US-20170207396-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-07-20 US disclosed
US-20170170408-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-06-15 US disclosed
US-20170170408-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-06-15 US disclosed
US-20170117488-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-04-27 US disclosed
US-20170117488-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO4C1, SLCO2A1 KDM4E 3376/4885L3MBTL1 3718/4885ATM 4360/4885
US-11527728-B2 Organic electroluminescent compounds and organic electroluminescent device comprising the same VDAC1, VDAC2, VAPA KDM4E 2458/4885L3MBTL1 300/4885ATM 2686/4885
US-20220102633-A1 ORGANIC ELECTROLUMINESCENT DEVICE SOD1, TRPC6, L1CAM KDM4E 2489/4885L3MBTL1 62/4885ATM 3395/4885
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 KDM4E 3745/4885L3MBTL1 3258/4885ATM 4632/4885
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 KDM4E 3745/4885L3MBTL1 3258/4885ATM 4632/4885
US-11917907-B2 Organic electroluminescent device SOD1, TRPC6, L1CAM KDM4E 2489/4885L3MBTL1 62/4885ATM 3395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.